Ankara Numune Education and Research Hospital, Department of Endocrinology, Sıhhiye, 06622 Ankara, Turkey.
Int J Endocrinol. 2013;2013:821745. doi: 10.1155/2013/821745. Epub 2013 May 22.
Aim. This study compares the effectiveness of Michigan Neuropathy Screening Instrument (MNSI), neurothesiometer, and electromyography (EMG) in detecting diabetic peripheral neuropathy in patients with diabetes type 2. Materials and Methods. 106 patients with diabetes type 2 treated at the outpatient clinic of Ankara Numune Education and Research Hospital Department of Endocrinology between September 2008 and May 2009 were included in this study. Patients were evaluated by glycemic regulation tests, MNSI (questionnaire and physical examination), EMG (for detecting sensorial and motor defects in right median, ulnar, posterior tibial, and bilateral sural nerves), and neurothesiometer (for detecting alterations in cold and warm sensations as well as vibratory sensations). Results. According to the MNSI score, there was diabetic peripheral neuropathy in 34 (32.1%) patients (score ≥2.5). However, when the patients were evaluated by EMG and neurothesiometer, neurological impairments were detected in 49 (46.2%) and 79 (74.5%) patients, respectively. Conclusion. According to our findings, questionnaires and physical examination often present lower diabetic peripheral neuropathy prevalence. Hence, we recommend that in the evaluation of diabetic patients neurological tests should be used for more accurate results and thus early treatment options to prevent neuropathic complications.
目的。本研究比较了密歇根神经病变筛查工具(MNSI)、神经感觉计和肌电图(EMG)在检测 2 型糖尿病患者周围神经病变中的有效性。
材料和方法。本研究纳入了 2008 年 9 月至 2009 年 5 月在安卡拉努姆恩教育与研究医院内分泌科门诊治疗的 106 例 2 型糖尿病患者。患者通过血糖调节试验、MNSI(问卷和体格检查)、EMG(用于检测右侧正中神经、尺神经、胫后神经和双侧腓肠神经的感觉和运动缺陷)和神经感觉计(用于检测冷觉和温觉以及振动觉的改变)进行评估。
结果。根据 MNSI 评分,34 例(32.1%)患者存在周围神经病变(评分≥2.5)。然而,当通过 EMG 和神经感觉计评估患者时,分别有 49 例(46.2%)和 79 例(74.5%)患者出现神经功能障碍。
结论。根据我们的发现,问卷和体格检查常显示出较低的周围神经病变发生率。因此,我们建议在评估糖尿病患者时,应使用神经学检查以获得更准确的结果,并尽早选择治疗方案以预防神经并发症。