Dimitrow Maarit, Leikola Saija, Kivelä Sirkka-Liisa, Airaksinen Marja, Mykkänen Sanna, Puustinen Juha
Vantaa V apteekki, ja Helsingin yliopisto, farmasian tiedekunta, sosiaalifarmasian osasto.
Duodecim. 2013;129(11):1159-66.
Inappropriate medication use among the aged review of the criteria Several criteria have been developed to assess inappropriate prescribing among individuals aged > or = 65 years. The criteria are classified as explicit (criterion-based) or implicit (judgment-based) and most of them have been validated using consensus methods. The criteria are based on risk-benefit definition of appropriateness; benzodiazepines and anticholinergics being the most often listed inappropriate medications. Many criteria also list inappropriate medication use due to drug-disease or drug-syndrome interactions. Avoiding unnecessary duplication is mentioned in the newest criteria. Fimea's database of medication for the elderly has been developed to support rational geriatric pharmacotherapy in Finnish healthcare. In addition to Fimea's database national evidence-based Current Care Guidelines on geriatric pharmacotherapy are needed.
标准综述 已制定了多项标准来评估65岁及以上人群的不适当处方。这些标准分为明确的（基于标准的）或隐含的（基于判断的），并且大多数已通过共识方法进行了验证。这些标准基于适当性的风险效益定义；苯二氮䓬类药物和抗胆碱能药物是最常被列为不适当的药物。许多标准还列出了由于药物-疾病或药物-综合征相互作用导致的不适当用药情况。最新标准中提到了避免不必要的重复。芬兰药品管理局（Fimea）的老年人药物数据库已开发出来，以支持芬兰医疗保健中的合理老年药物治疗。除了Fimea的数据库外，还需要基于国家证据的老年药物治疗现行护理指南。
