Thiem U
Klinik für Altersmedizin und Frührehabilitation, Marienhospital Herne, Klinik der Ruhr-Universität Bochum, Widumer Str. 8, 44627 Herne, Deutschland.
Internist (Berl). 2012 Sep;53(9):1125-30. doi: 10.1007/s00108-012-3087-5.
Potentially inappropriate medication (PIM) in the elderly is a common problem in primary care. Depending on the setting under investigation, recent studies reported a prevalence of PIM up to 24% in Germany. In 2010 the German national PRISCUS list containing explicit criteria to identify PIM was published. First data show a possible association between PIM as defined by the Priscus list and negative health outcomes. However, prospective controlled trials are needed to assess whether interventions based on explicit criteria are able to improve patient-related outcome. Against this backdrop, the present review comments on recent data, especially those with impact for the German health care system.
老年人潜在不适当用药（PIM）是基层医疗中的常见问题。根据所调查的环境，最近的研究报告称，德国PIM的患病率高达24%。2010年，德国发布了包含明确识别PIM标准的国家PRISCUS清单。初步数据显示，Priscus清单定义的PIM与负面健康结果之间可能存在关联。然而，需要进行前瞻性对照试验，以评估基于明确标准的干预措施是否能够改善患者相关结局。在此背景下，本综述对近期数据进行评论，尤其是那些对德国医疗保健系统有影响的数据。
