Mao Wen-Chao, Liu Bao-Yan, He Li-Yun, Liu Zhi-Shun
Institute of Basic Research of Clinical Medicine, China Academy of Chinese Medical Sciences, Beijing 100700, China; 2. China Academy of Chinese Medical.
Zhongguo Zhen Jiu. 2013 Apr;33(4):367-71.
Differences and relations between effects of acupuncture therapy and sham acupuncture are systematically analyzed in this article through the influential factors of acupuncture effect. And it is held that sham acupuncture effect is not exactly equal to placebo effect. The effects of both acupuncture and sham acupuncture are composed by specific effects and non-specific effects, and the differences of non-specific effects between acupunc ture and sham acupuncture can be minimized furthest with blinding and randomized method. Therefore, the difference of acupuncture and sham acupuncture treatment rests with the degree of differences of the specific effects. Only when both of the specific effect of acupuncture and the effect of acupuncture are minimized, can it be applied as the ideal placebo control. Consequently when placebo acupunture are setted up, factors such as the body condition, site of stimulation and stimulation parameters which can influence the specific effect of acupuncture should be taken into consideration to produce the relatively minimum specific effect.
本文通过针刺效应的影响因素，系统分析了针刺疗法与假针刺效应之间的差异及关系。并认为假针刺效应并不完全等同于安慰剂效应。针刺和假针刺的效应均由特异性效应和非特异性效应组成，采用盲法和随机化方法可最大程度地减少针刺与假针刺非特异性效应之间的差异。因此，针刺与假针刺治疗的差异在于特异性效应的差异程度。只有当针刺的特异性效应和针刺效应都最小化时，才能将其用作理想的安慰剂对照。因此，在设置安慰剂针刺时，应考虑身体状况、刺激部位和刺激参数等可能影响针刺特异性效应的因素，以产生相对最小的特异性效应。
