[I-125 labeling of human, rat, and bovine fibrinogen].
作者信息
Richter M, Cyranka U, Markwardt F
机构信息
Institut für Pharmakologie und Toxikologie, Medizinischen Akademie Erfurt.
出版信息
Pharmazie. 1990 Mar;45(3):200-3.
PMID:2381963
Abstract
Human, rat and bovine fibrinogen were radioiodinated using a modified chloramine-T method under mild labelling conditions and with a satisfactory labelling efficiency. The 125I-human, rat and bovine fibrinogen preparations obtained met the requirements with respect to clottability, low content of 125Iodide as well as stability in vitro and in vivo. SDS-PAGE mobility demonstrated that the integrity of the fibrinogen molecule was not affected by the labelling procedure.
摘要
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