Leiden University Medical Centre, Department of Public Health and Primary Care, Leiden, the Netherlands.
Addiction. 2013 Dec;108(12):2183-92. doi: 10.1111/add.12289. Epub 2013 Aug 14.
To examine the impact of two national tobacco control interventions in the past decade on (dispensed) prescriptions of stop-smoking medication.
Ecological study with interrupted time-series analyses of quarterly data points of three nation-wide representative databases.
The Netherlands 2001-2012, with the introduction of the guideline for smoking cessation care for general practitioners (GP) in 2007 and full insurance coverage for smoking cessation treatment in 2011.
GPs, pharmacists and people in the general population aged 15 years and older.
Time-series plots were inspected visually and segmented regression analyses were performed to estimate the change in level and slope of (dispensed) prescriptions of stop-smoking medication and smoking prevalence in the years preceding and after the tobacco control interventions.
No measurable effects of the GP guideline on (dispensed) prescriptions were observed. Shortly after the start of health insurance coverage, an estimated increase in primary care prescriptions of 6.3 per 1000 smokers [95% confidence interval (CI) = 2.9-9.8; P = 0.001] and 17.3 dispensed items per 1000 smokers (95% CI = 12.5-22.0; P < 0.000) was accompanied by a sudden drop in smoking prevalence of 2.9% (95% CI = 4.6-1.1; P = 0.002) in the first quarter of 2011. Immediately after the coverage abolition, smoking prevalence increased by 1.2% (95% CI = 0.5-2.8; P = 0.156) and dispensed prescription rates decreased with 21.6 per 1000 smokers (95% CI = 26.0-17.2; P < 0.000).
Full health insurance coverage for smoking cessation treatment in the Netherlands was accompanied by a significant increase in the number of (dispensed) prescriptions of stop-smoking medication and a decrease in smoking prevalence.
研究过去十年中两项国家控烟干预措施对戒烟药物处方(配药)的影响。
对三个全国代表性数据库的季度数据点进行的生态学研究,采用中断时间序列分析。
荷兰,2001-2012 年,2007 年推出了全科医生戒烟护理指南,2011 年全面覆盖戒烟治疗费用。
全科医生、药剂师和 15 岁及以上的普通人群。
通过视觉检查时间序列图,并进行分段回归分析,以估计在烟草控制干预措施实施之前和之后的几年中,戒烟药物处方(配药)和吸烟率的变化水平和斜率。
未观察到全科医生指南对(配药)处方的可衡量影响。在健康保险覆盖开始后不久,初级保健处方中估计每 1000 名吸烟者增加 6.3 剂[95%置信区间(CI)=2.9-9.8;P=0.001]和 17.3 个配药项目每 1000 名吸烟者(95%CI=12.5-22.0;P<0.000),同时吸烟率在 2011 年第一季度突然下降 2.9%(95%CI=4.6-1.1;P=0.002)。在覆盖取消后不久,吸烟率增加了 1.2%(95%CI=0.5-2.8;P=0.156),配药率下降了 21.6 剂每 1000 名吸烟者(95%CI=26.0-17.2;P<0.000)。
荷兰全面的戒烟治疗健康保险覆盖伴随着戒烟药物处方(配药)数量的显著增加和吸烟率的下降。