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全科医生对急性食物过敏反应的管理。

Management of acute food allergic reactions by general practitioners.

作者信息

Klemans R J B, Le T-M, Sigurdsson V, Enters-Weijnen C F, van Hoffen E, Bruijnzeel-Koomen C A F M, Knulst A C

机构信息

Department of Dermatology/Allergology, University Medical Center Utrecht, The Netherlands.

出版信息

Eur Ann Allergy Clin Immunol. 2013 Apr;45(2):43-51.

Abstract

BACKGROUND

Food is one of the leading causes of anaphylaxis. In the Netherlands, patients visit a general practitioner (GP) as often as an emergency department (ED) in case of an acute food allergic reaction. So far, the management of food allergic reactions by GPs has not been investigated. Therefore, we explored the management of acute food allergic reactions by GPs regarding specific treatment, observation period, prescription of emergency medication to treat new episodes, diet advices and referral to a specialist.

METHODS

A questionnaire containing three hypothetical cases (two anaphylactic and one mild case) with questions about their management was sent to 571 GPs.

RESULTS

Overall, treatment choice was dependent on the severity of the reaction (mild vs. anaphylaxis, P < .001). However, epinephrine was used for treatment of anaphylaxis with mainly respiratory symptoms in only 27% and for anaphylaxis with mainly cardiovascular symptoms in 73%. At discharge, the percentages for prescription of self-injectable epinephrine were 53% and 77%, respectively. A short observation period of <2 hours was advised by 42% of general practitioners in case of anaphylaxis.

CONCLUSIONS

Treatment of food induced anaphylaxis by GPs appears to be suboptimal: a considerable number of patients would not be treated with epinephrine for the acute reaction (especially anaphylactic cases with respiratory symptoms), the observation period chosen by GPs was often too short and self-injectable epinephrine was not always prescribed at discharge to treat possible new episodes. Education programs are needed to increase the awareness of GPs to recognize and treat anaphylactic reactions.

摘要

背景

食物是过敏反应的主要诱因之一。在荷兰,急性食物过敏反应患者前往全科医生(GP)处就诊的频率与前往急诊科(ED)就诊的频率相当。到目前为止,尚未对全科医生对食物过敏反应的管理进行研究。因此,我们探讨了全科医生对急性食物过敏反应的管理情况,包括具体治疗方法、观察期、治疗新发作的急救药物处方、饮食建议以及转诊至专科医生等方面。

方法

向571名全科医生发送了一份包含三个假设病例(两个过敏反应病例和一个轻度病例)及关于其管理问题的问卷。

结果

总体而言,治疗选择取决于反应的严重程度(轻度与过敏反应,P <.001)。然而,肾上腺素仅用于27%主要有呼吸道症状的过敏反应治疗,用于73%主要有心血管症状的过敏反应治疗。出院时,自行注射肾上腺素的处方比例分别为53%和77%。42%的全科医生建议在过敏反应情况下观察期<2小时。

结论

全科医生对食物诱发的过敏反应的治疗似乎并不理想:相当多的患者在急性反应时不会接受肾上腺素治疗(尤其是有呼吸道症状的过敏反应病例),全科医生选择的观察期往往过短,出院时并非总是开具自行注射肾上腺素以治疗可能的新发作。需要开展教育项目以提高全科医生识别和治疗过敏反应的意识。

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