Jung Ui-Won, Kim Sungtae, Lee In-Kyeong, Kim Min-Soo, Lee Jung-Seok, Kim Hee-Jin
Department of Periodontology, Research Institute for Periodontal Regeneration, College of Dentistry, Yonsei University, Seoul, Korea.
Clin Oral Implants Res. 2014 Oct;25(10):1169-74. doi: 10.1111/clr.12226. Epub 2013 Jul 4.
The objective of this study was to evaluate the secondary stability of microthickness hydroxyapatite (HA)-coated implants placed without primary stability in dogs.
A total of 48 implants were placed in six dogs. The groups were divided according to the absence or presence of primary stability and healing periods (4 and 8 weeks). Two implants for histological analysis and removal torque test in experimental group were placed without primary stability, showing rotational movement. The other two implants in control group were placed with primary stability. Mechanical test values and histometric measurements were analyzed.
The experimental group showed significant increase in a time-dependent manner, while the mean values of the control group were constant in the mechanical tests. The HA layer remained intact, and substantial bone fragments were attached on the surface of the retrieved implant. All implants appeared to be in intimate contact with the host bone and without any inflammation after both 4 and 8 weeks of healing in histology.
The HA-coated implants exhibited mechanically and histometrically comparable osseointegration after 4 weeks of healing, regardless of primary stability, and the HA-coating layer demonstrated high resistance to exfoliation.
本研究的目的是评估在犬体内无初期稳定性植入的微厚度羟基磷灰石（HA）涂层种植体的二期稳定性。
在6只犬体内共植入48枚种植体。根据有无初期稳定性和愈合期（4周和8周）进行分组。实验组有2枚种植体在植入时无初期稳定性，表现为旋转移动，用于组织学分析和取出扭矩测试。对照组的另外2枚种植体植入时具有初期稳定性。对力学测试值和组织计量学测量结果进行分析。
实验组呈现出随时间的显著增加，而对照组在力学测试中的平均值保持恒定。HA涂层保持完整，取出的种植体表面附着有大量骨碎片。组织学检查显示，愈合4周和8周后，所有种植体似乎都与宿主骨紧密接触且无任何炎症。
无论初期稳定性如何，HA涂层种植体在愈合4周后在力学和组织计量学上均表现出可比的骨整合，且HA涂层表现出高抗剥脱性。
