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妊娠合并肺转移的绒毛膜癌经化疗后成功分娩及预后情况

Choriocarcinoma with lung metastases during pregnancy with successful delivery and outcome after chemotherapy.

作者信息

Nabers J, Splinter T A, Wallenburg H C, ten Kate F J, Oosterom R, Hilvering C

机构信息

Department of Pulmonary Medicine, University Hospital Dijkzigt, Rotterdam, The Netherlands.

出版信息

Thorax. 1990 May;45(5):416-8. doi: 10.1136/thx.45.5.416.

Abstract

A patient with an intrauterine pregnancy of 27 weeks had a coexisting pulmonary metastatic choriocarcinoma. On the chest radiograph the lung metastases appeared as pulmonary infiltrates, simulating atypical pneumonia. Serum human chorionic gonadotrophin levels were normal for gestational age. Treatment with methotrexate was successful. This is the first reported case of choriocarcinoma in a woman with a pregnancy of less than 35 weeks in which both mother and child survived. The case emphasises the need to consider choriocarcinoma in any pregnant woman who presents with haemoptysis and pulmonary nodules or infiltrates.

摘要

一名妊娠27周的孕妇合并肺转移性绒毛膜癌。胸部X线片显示肺部转移灶表现为肺部浸润,类似非典型肺炎。血清人绒毛膜促性腺激素水平在孕龄时正常。甲氨蝶呤治疗成功。这是首例报道的妊娠不足35周的女性绒毛膜癌病例,母婴均存活。该病例强调,对于任何出现咯血及肺结节或浸润的孕妇,都需要考虑绒毛膜癌的可能性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/978e/462498/a349ade049a0/thorax00341-0077-a.jpg

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