a Kharvel Subharti College of Pharmacy, Swami Vivekanand Subharti University , Meerut , India.
Nat Prod Res. 2014;28(4):230-8. doi: 10.1080/14786419.2013.814054. Epub 2013 Jul 4.
Phytochemical study on the methanolic extract of Caesalpinia crista afforded two novel compounds, 2-hydroxytrideca-3,6-dienyl-pentanoate and octacosa-12,15-diene along with known compounds 3-O-methylellagic acid 3'O-α-rhamnopyranoside, β-sitosterol and sucrose. Compound 3-O-methylellagic acid 3'O-α-rhamnopyranoside is reported for the first time from the plant. Molecular structures, of isolated compounds, were elucidated by using the NMR spectroscopy in combination with IR and mass spectral data. All isolated compounds, extract and fractions were evaluated for in vitro antibacterial activity against various Gram-positive and Gram-negative bacterial strains and found to be significantly active against Staphylococcus aureus and methicillin-resistant S. aureus (minimum inhibitory concentration: 64-512 μg mL(- 1)).
从金合欢属植物的甲醇提取物中分离得到两种新化合物，2-羟基十三-3,6-二烯基戊酸酯和二十八碳-12,15-二烯，以及已知化合物 3-O-甲基鞣花酸 3'O-α-鼠李吡喃糖苷、β-谷甾醇和蔗糖。化合物 3-O-甲基鞣花酸 3'O-α-鼠李吡喃糖苷首次从该植物中分离得到。通过使用 NMR 光谱结合 IR 和质谱数据阐明了分离化合物的分子结构。所有分离得到的化合物、提取物和馏分均进行了体外抗菌活性评价，结果表明它们对各种革兰氏阳性和革兰氏阴性菌具有显著的活性，对金黄色葡萄球菌和耐甲氧西林金黄色葡萄球菌的最小抑菌浓度为 64-512μg/mL。
