提出并验证一个快速问题，以评估在老年流行病学研究中阳光暴露对维生素 D 的影响。
Proposal and validation of a quick question to rate the influence of sun exposure in geriatric epidemiological studies on vitamin D.
机构信息
Department of Neuroscience, Division of Geriatric Medicine, Angers University Hospital, Angers University Memory Clinic, UNAM, Angers, France.
出版信息
Int J Vitam Nutr Res. 2012 Dec;82(6):412-6. doi: 10.1024/0300-9831/a000139.
BACKGROUND
Vitamin D is synthesized in the skin under the action of solar ultraviolet-B radiation. The objective of this study was to determine whether a simple question exploring sun exposure ("When weather is nice, do you stay more than 15 minutes exposed to the sun (face and hands uncovered) between 11am and 3pm?") could be associated with serum 25-hydroxyvitamin D status among 751 older community-dwelling women (mean age, 80.2 ± 3.5 years).
METHODS
Two groups were distinguished based on the binary "Yes" versus "No" answer. Hypovitaminosis D was defined as serum 25-hydroxyvitamin D < 30 ng/mL.
RESULTS
Fewer women with hypovitaminosis D answered "Yes" to the question on sun exposure (p = 0.042). Answering "Yes" was inversely associated with hypovitaminosis D (OR = 0.56, p = 0.049) after adjustment for demographic characteristics and exogenous sources of vitamin D, with a positive predictive value of 88 %.
CONCLUSION
This simple question may reflect the sun's influence on vitamin D status and identify older community-dwellers with hypovitaminosis D.
背景
维生素 D 在太阳紫外线-B 辐射的作用下于皮肤中合成。本研究旨在确定一个简单的问题，即“当天气好时，您是否会在上午 11 点到下午 3 点之间（面部和手部暴露在外），超过 15 分钟暴露在阳光下？”，是否与 751 名年龄在 80.2 ± 3.5 岁之间的社区居住的老年女性的血清 25-羟维生素 D 状态有关。
方法
根据“是”与“否”的答案将两组区分开来。维生素 D 缺乏症定义为血清 25-羟维生素 D < 30ng/mL。
结果
维生素 D 缺乏症的女性回答“是”的比例较低（p = 0.042）。在调整人口统计学特征和外源性维生素 D 来源后，回答“是”与维生素 D 缺乏症呈负相关（OR = 0.56，p = 0.049），其阳性预测值为 88%。
结论
这个简单的问题可能反映了阳光对维生素 D 状态的影响，并可识别出维生素 D 缺乏症的社区居住的老年女性。
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