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五种禽波氏杆菌血清型对鸡气管上皮细胞的黏附。

Adherence of five serovars of Ornithobacterium rhinotracheale to chicken tracheal epithelial cells.

机构信息

Department of Microbiology of the National School of Biological Sciences -IPN , Prolongación de Carpio y Plan de Ayala s/n. Col. Casco de Santo Tomas, C.P. 11340, Mexico City.

出版信息

Br Poult Sci. 2013;54(4):425-9. doi: 10.1080/00071668.2013.800942. Epub 2013 Jul 4.

DOI:10.1080/00071668.2013.800942
PMID:23826883
Abstract
  1. Interaction between bacteria and host tissue is important, both for primary adhesion and tissue-specific colonisation, as well as for pathogen invasion for different host tissues. 2. Ornithobacterium rhinotracheale is a bacterium associated with respiratory tract infections in poultry. The mechanisms by which O. rhinotracheale causes infection are not known. To date, at least 18 serovars of this bacterium, with or without the ability to agglutinate erythrocytes of chicken and other species, have been identified. 3. The purpose of this work was to evaluate the ability of five references strains, belonging to serovars A, B, C, D and E, to adhere to a culture of primary chicken tracheal cells. 4. Serovars A and B adhered to less than 20% of tracheal cells with no specific adherence pattern. Serovars C, D and E gave adherence values greater than 70%. Serovars C and E showed a diffuse adherence pattern, while serovar D had an aggregated adherence pattern. 5. The adherence ability and pattern could be associated with different pathogenicity mechanisms in the various serovars but more studies are needed to understand the reasons for these differences.
摘要
  1. 细菌与宿主组织之间的相互作用非常重要,无论是对于初次黏附还是组织特异性定植,还是对于不同宿主组织的病原体入侵而言都是如此。

  2. 滑液支原体是一种与家禽呼吸道感染相关的细菌。目前还不知道滑液支原体引起感染的机制。迄今为止,已经鉴定出至少 18 种血清型的该细菌,这些血清型有些具有凝集鸡和其他物种红细胞的能力,有些则没有。

  3. 本研究的目的是评估 5 株参考菌株(血清型 A、B、C、D 和 E)黏附原代鸡气管细胞的能力。

  4. 血清型 A 和 B 黏附于不到 20%的气管细胞,没有特定的黏附模式。血清型 C、D 和 E 的黏附值大于 70%。血清型 C 和 E 表现出弥散的黏附模式,而血清型 D 则表现出聚集的黏附模式。

  5. 黏附能力和模式可能与不同血清型的不同致病性机制有关,但需要进一步研究以了解这些差异的原因。

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