研究胶原蛋白和维生素对钛表面仿生羟基磷灰石涂层形成的影响。

Investigation on the effect of collagen and vitamins on biomimetic hydroxyapatite coating formation on titanium surfaces.

机构信息

Gheorghe Asachi Technical University of Iasi, Faculty of Chemical Engineering and Environmental Protection, Prof. dr. docent Dimitrie Mangeron Rd., no. 63, zip: 700050, Iasi, Romania.

出版信息

Mater Sci Eng C Mater Biol Appl. 2013 Apr 1;33(3):1683-8. doi: 10.1016/j.msec.2012.12.080. Epub 2012 Dec 31.

DOI:10.1016/j.msec.2012.12.080

PMID:23827624

Abstract

This study uses an in vitro experimental approach to investigate the roles of collagen and vitamins in regulating the deposition of hydroxyapatite layer on the pure titanium surface. Titanium implants were coated with a hydroxyapatite layer under biomimetic conditions by using a supersaturated calcification solution (SCS), modified by adding vitamins A and D3, and collagen. The hydroxyapatite deposits on titanium were investigated by means of scanning electron microscopy (SEM) coupled with X-ray analysis (EDX), X-ray photoelectron spectroscopy (XPS), X-ray diffraction (XRD) and Fourier transformed infrared (FTIR) spectroscopy. The results obtained have shown that hydroxyapatite coatings were produced in vitro under vitamins and collagen influence.

摘要

本研究采用体外实验方法，探讨胶原和维生素在调节纯钛表面羟磷灰石层沉积中的作用。通过使用过饱和钙化溶液（SCS），并添加维生素 A 和 D3 以及胶原对其进行改性，在仿生条件下在钛植入物上涂覆羟磷灰石层。通过扫描电子显微镜（SEM）结合 X 射线分析（EDX）、X 射线光电子能谱（XPS）、X 射线衍射（XRD）和傅里叶变换红外（FTIR）光谱对钛上的羟磷灰石沉积物进行了研究。结果表明，在维生素和胶原的影响下，体外产生了羟磷灰石涂层。