Weber Katja S, Defosse Jerome M, Wappler Frank, Sakka Samir G
Klinik für Anästhesiologieund operative Intensivmedizin, Krankenhaus Köln-Merheim.
Anasthesiol Intensivmed Notfallmed Schmerzther. 2013 Jun;48(6):386-90. doi: 10.1055/s-0033-1349001. Epub 2013 Jul 4.
Clostridium difficile infections (CDI) are increasing in incidence and severity, amongst other reasons because of the increasing spread of hypervirulent strains. Leukocytosis is a sign of severe CDI and is predictive for a complicated course. In this case report, we describe 2 patients with CDI who developed leukocytosis within a leukemoid range. In both cases high white blood cell counts returned totally to normal range under CDI therapy according to guidelines. Leukemia-related therapy patterns were not needed. Notably, in none of the patients a hypervirulent strain was isolated.
