Lejtzén Nadja, Sundquist Jan, Sundquist Kristina, Li Xinjun
Center for Primary Health Care Research, Clinical Research Centre (CRC), Building 28, Entrance 72, Jan Waldenströms gata 35, Skåne University Hospital, Lund University, 205 02, Malmö, Sweden.
Eur Arch Psychiatry Clin Neurosci. 2014 Apr;264(3):235-45. doi: 10.1007/s00406-013-0422-3. Epub 2013 Jul 5.
The aim of this study was to estimate the prevalence and incidence of mood disorders, anxiety disorders, and stress and adjustment disorders in primary health care in Sweden and to analyse the relationship between socioeconomic and demographic factors and incidence of these disorders. Prevalence and incidence data on the study population was retrieved from a Swedish primary health care database. A cohort study design was used to examine the incidence of, and risk factors for, mood disorders, anxiety disorders, and stress and adjustment disorders. Cox regression models were used in the statistical analyses. The overall 12-month prevalence of these clinically diagnosed disorders was 2.4 % (3.2 % in women and 1.5 % in men). The overall incidence was 18.4 per 1,000 person-years. The strongest sociodemographic risk factors for these disorders were female gender (HR = 2.04), low family income (HR = 1.52), living in a large city (HR = 1.37), and age 35-44 years (HR = 1.20). This large-scale study examined the prevalence and incidence of common psychiatric disorders diagnosed in primary health care, as well as the potential influence of sociodemographic factors on these disorders. The information obtained is useful for clinicians in primary health care and decision-makers.
本研究的目的是估计瑞典初级卫生保健中情绪障碍、焦虑障碍以及应激与适应障碍的患病率和发病率,并分析社会经济和人口因素与这些障碍发病率之间的关系。研究人群的患病率和发病率数据取自瑞典初级卫生保健数据库。采用队列研究设计来考察情绪障碍、焦虑障碍以及应激与适应障碍的发病率和危险因素。统计分析中使用了Cox回归模型。这些临床诊断障碍的总体12个月患病率为2.4%(女性为3.2%,男性为1.5%)。总体发病率为每1000人年18.4例。这些障碍最主要的社会人口危险因素为女性(风险比=2.04)、家庭收入低(风险比=1.52)、居住在大城市(风险比=1.37)以及35 - 44岁(风险比=1.20)。这项大规模研究考察了初级卫生保健中诊断出的常见精神障碍的患病率和发病率,以及社会人口因素对这些障碍的潜在影响。所获得的信息对初级卫生保健中的临床医生和决策者有用。