Tedrus Gloria Maria de Almeida Souza, Fonseca Lineu Corrêa, Carvalho Rachel Marin
Faculdade de Medicina, PUC-Campinas, Campinas,SP, Brazil.
Arq Neuropsiquiatr. 2013 Jun;71(6):385-91. doi: 10.1590/0004-282X20130044.
Objective To study socio-demographic and clinical aspects, as well as psychiatric co-morbidity that influence the quality of life of adult epileptic patients. Methods One hundred and thirty-two individuals diagnosed with epilepsy were evaluated from neurological/clinical and psychiatric points of view and by the Quality of Life in Epilepsy Inventory (QOLIE-31). Predictive factors for the QOLIE-31 scores were studied. Results The regression analyses indicated the existence of psychiatric co-morbidity (total score, seizure worry, emotional well-being, energy/fatigue, social function and cognitive function) and a greater seizure frequency (total score, cognitive function and energy/fatigue) as predictive factors for lower scores in the total QOLIE-31 score and in various dimensions. Abnormalities in the neurological exam and poly-therapy with anti-epileptic drugs were negative factors limited to one of the dimensions cognitive function and social function, respectively. Conclusion The presence of psychiatric co-morbidity and a greater seizure frequency were the main factors influencing the quality of life in epileptic patients as evaluated by QOLIE-31.
目的 研究影响成年癫痫患者生活质量的社会人口学和临床因素，以及精神共病情况。方法 从神经学/临床和精神科角度，采用癫痫生活质量量表（QOLIE-31）对132例确诊为癫痫的患者进行评估。研究QOLIE-31评分的预测因素。结果 回归分析表明，精神共病（总分、癫痫担忧、情绪健康、精力/疲劳、社会功能和认知功能）以及较高的癫痫发作频率（总分、认知功能和精力/疲劳）是QOLIE-31总分及各维度得分较低的预测因素。神经学检查异常和抗癫痫药物联合治疗分别是仅限于认知功能和社会功能维度的负面因素。结论 根据QOLIE-31评估，精神共病的存在和较高的癫痫发作频率是影响癫痫患者生活质量的主要因素。
