一种用于测定血清肌酐的改进型阳离子交换高效液相色谱法。
An improved cation exchange HPLC method for the measurement of serum creatinine.
作者信息
Guy J M, Legg E F
机构信息
Department of Clinical Chemistry, East Birmingham Hospital, Bordesley Green East, UK.
出版信息
Ann Clin Biochem. 1990 May;27 ( Pt 3):223-6. doi: 10.1177/000456329002700307.
PMID:2382956
Abstract
An improved HPLC method for the measurement of serum creatinine is described. Separation is effected using a strong cation exchange column at pH 4.7. Analytical recovery, precision and linearity are satisfactory, and the method correlates well with a kinetic Jaffé procedure. The method provides a means of accurately measuring creatinine and may be of use in the investigation of interference in creatinine assays.
摘要
描述了一种改进的用于测定血清肌酐的高效液相色谱法。使用强阳离子交换柱在pH 4.7条件下进行分离。分析回收率、精密度和线性均令人满意，且该方法与动力学Jaffé法相关性良好。该方法提供了一种准确测量肌酐的手段，可用于研究肌酐测定中的干扰情况。
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