Sawanyawisuth Kittisak, Chotmongkol Verajit
Department of Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand.
Handb Clin Neurol. 2013;114:207-15. doi: 10.1016/B978-0-444-53490-3.00015-7.
Eosinophilic meningitis is defined by the presence of at least 10% eosinophils in the total cerebrospinal fluid (CSF) leukocyte count. Although there are several possible causes of eosinophils in the CSF, parasitic infection is the main cause. The three common parasites causing eosinophilic meningitis include Angiostrongylus cantonensis, Gnathostoma spinigerum, and Taenia solium. Even though these parasites are endemic in tropical countries, they are now spreading globally due to extensive traveling, and physicians worldwide should pay more attention to this condition. This chapter will review risk factors, clinical manifestations, and treatment of these three parasites.
嗜酸性粒细胞性脑膜炎的定义是,脑脊液(CSF)白细胞计数中嗜酸性粒细胞至少占10%。虽然脑脊液中出现嗜酸性粒细胞有多种可能原因,但寄生虫感染是主要原因。引起嗜酸性粒细胞性脑膜炎的三种常见寄生虫包括广州管圆线虫、棘颚口线虫和猪带绦虫。尽管这些寄生虫在热带国家为地方性流行,但由于广泛的旅行,它们现在正在全球传播,世界各地的医生应更多地关注这种情况。本章将综述这三种寄生虫的危险因素、临床表现和治疗方法。