Chen C J, Wu H Y, Chuang Y C, Chang A S, Luh K T, Chao H H, Chen K Y, Chen S G, Lai G M, Huang H H
Institute of Public Health, National Taiwan University College of Medicine, Taipei.
Anticancer Res. 1990 Jul-Aug;10(4):971-6.
The specific aim of this study was to examine epidemiologic characteristics and multiple risk factors of lung cancer in Taiwan. The age-adjusted mortality from lung cancer has been increasing since the early 1950s with a constant male-to-female ratio of around 2.0. International comparison of cumulative mortality from lung cancer showed a much lower male-to-female ratio in Chinese than in other populations. Significantly high mortality from lung cancer was observed in highly urbanized cities and the endemic area of chronic arsenicism in Taiwan. Significant associations of active and passive cigarette smoking with epidermoid carcinoma, small cell carcinoma and adenocarcinoma of the lung were observed in a hospital-based case-control study carried out in Taipei metropolitan areas. Alcohol drinking, coffee drinking and various types of indoor air pollution were not related to lung cancer after the cigarette smoking habit was adjusted through a multiple logistic regression analysis.
本研究的具体目的是调查台湾地区肺癌的流行病学特征和多种风险因素。自20世纪50年代初以来，肺癌的年龄调整死亡率一直在上升，男女比例一直保持在2.0左右。肺癌累积死亡率的国际比较显示，中国人的男女比例远低于其他人群。在台湾高度城市化的城市和慢性砷中毒流行地区，观察到肺癌死亡率显著偏高。在台北都会区进行的一项基于医院的病例对照研究中，观察到主动和被动吸烟与肺表皮样癌、小细胞癌和腺癌之间存在显著关联。通过多元逻辑回归分析调整吸烟习惯后，饮酒、喝咖啡和各种类型的室内空气污染与肺癌无关。
