Laboratory of Pathology, Heart Institute (InCor), Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil.
Cardiovasc Pathol. 2013 Nov-Dec;22(6):505-7. doi: 10.1016/j.carpath.2013.05.003. Epub 2013 Jul 2.
A 54-year-old male entered the emergency room in cardiorespiratory arrest after syncope at home. Resuscitation was attempted, but the patient died a few hours later. At necropsy, aneurysms were found at the right and left anterior descending coronary arteries. At microscopic examination, there was no significant coronary atherosclerosis, and a dense inflammatory infiltrate was detected, with a high number of igG4-positive cells (94.0 positive cells/hpf). The case illustrates that IgG4-related disease can cause coronary disease and sudden cardiac death.
一位 54 岁男性在家晕厥后出现心搏呼吸骤停，被送入急诊室。虽经抢救，但数小时后患者死亡。尸检时发现患者左右前降支冠状动脉有动脉瘤。镜下检查未见明显冠状动脉粥样硬化，存在密集的炎症浸润，且 IgG4 阳性细胞数量较多（94.0 个阳性细胞/高倍视野）。该病例说明 IgG4 相关疾病可导致冠状动脉疾病和心源性猝死。
