School of Food Science and Biotechnology, Kyungpook National University, Daegu 702-701, Republic of Korea.
Enzyme Microb Technol. 2013 Aug 15;53(3):152-3. doi: 10.1016/j.enzmictec.2013.02.009. Epub 2013 Mar 19.
7,10-Dihydroxy-8(E)-octadecenoic acid (DOD), one of hydroxy fatty acids, was successfully produced from oleic acid and natural vegetable oils containing oleic acid by a bacterial strain Pseudomonas aeruginosa (PR3). However, biological properties of DOD remained unknown so far. In this study, as a trial to determine the biological properties of DOD molecule, antibacterial activities of DOD against plant pathogenic bacteria were determined qualitatively and quantitatively. DOD presented strong antibacterial activities against all the bacterial strains tested with MIC value being in the range of 125-1000μg/ml and there was no sensitivity preference detected between Gram-positive and Gram-negative strains.
7,10-二羟基-8(E)-十八烯酸（DOD）是一种羟基脂肪酸，可由油酸和含有油酸的天然植物油通过铜绿假单胞菌（PR3）成功生产。然而，DOD 的生物学特性至今仍不清楚。在这项研究中，作为确定 DOD 分子生物学特性的尝试，定性和定量测定了 DOD 对植物病原菌的抗菌活性。DOD 对所有测试的细菌菌株均表现出很强的抗菌活性，最低抑菌浓度（MIC）值在 125-1000μg/ml 范围内，并且在革兰氏阳性菌和革兰氏阴性菌之间没有检测到敏感性偏好。
