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[长期视频脑电图监测的安全性研究]

[Safety study of long-term video-electroencephalogram monitoring].

作者信息

Ley M, Vivanco R, Massot A, Jiménez J, Roquer J, Rocamora R

机构信息

Unidad de Monitorización de Epilepsia, Servicio de Neurología, Hospital del Mar, Parc de Salut Mar, Barcelona, España.

Unidad de Monitorización de Epilepsia, Servicio de Neurología, Hospital del Mar, Parc de Salut Mar, Barcelona, España.

出版信息

Neurologia. 2014 Jan-Feb;29(1):21-6. doi: 10.1016/j.nrl.2013.03.008. Epub 2013 Jul 3.

Abstract

INTRODUCTION

The increased morbidity and mortality and poorer quality of life associated with drug-resistant epilepsy justify admitting patients to epilepsy monitoring units (EMU). These units employ methods that promote the occurrence of seizures, which involves a risk of secondary adverse events. The aim of our study is to characterise and quantify these adverse events in a Spanish EMU.

MATERIALS AND METHODS

A descriptive, longitudinal and retrospective study of patients admitted consecutively to our EMU. Patients admitted due to status epilepticus, clusters of seizures, or as participants in a clinical trial were excluded.

RESULTS

We included 175 patients, of whom 92.1% (161) did not suffer any adverse events. Status epilepticus was present in 3.4% (6); 1.7% (3) had traumatic injury, 1.7% (3) had interictal or postictal psychosis, and 1.1% (2) had cardiorespiratory impairment. There were no risk factors associated with these adverse events.

CONCLUSIONS

The most frequently-identified adverse events were status epilepticus, traumatic injury, interictal or postictal psychosis, and cardiorespiratory disorders. The frequency of these adverse events was similar to that seen in international literature. The complications detected do not contraindicate VEEGM.

摘要

引言

耐药性癫痫所导致的发病率和死亡率上升以及生活质量下降,使得将患者收治入癫痫监测单元(EMU)成为合理之举。这些单元采用的方法会促使癫痫发作,这存在引发继发性不良事件的风险。我们研究的目的是对西班牙一家癫痫监测单元中的这些不良事件进行特征描述和量化。

材料与方法

对连续收治入我们癫痫监测单元的患者进行描述性、纵向和回顾性研究。因癫痫持续状态、癫痫发作簇或作为临床试验参与者而收治的患者被排除。

结果

我们纳入了175例患者,其中92.1%(161例)未发生任何不良事件。癫痫持续状态占3.4%(6例);1.7%(3例)有创伤性损伤,1.7%(3例)有发作间期或发作后精神病,1.1%(2例)有心肺功能损害。这些不良事件不存在相关危险因素。

结论

最常发现的不良事件是癫痫持续状态、创伤性损伤、发作间期或发作后精神病以及心肺疾病。这些不良事件的发生率与国际文献报道相似。检测到的并发症并不构成视频脑电图监测(VEEGM)的禁忌证。

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