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通过去除留置球囊优化胃静脉曲张球囊闭塞逆行静脉栓塞术(BRTO)的物流:概念与技术

Optimizing logistics for balloon-occluded retrograde transvenous obliteration (BRTO) of gastric varices by doing away with the indwelling balloon: concept and techniques.

作者信息

Saad Wael E, Nicholson David B

机构信息

Division of Vascular and Interventional Radiology, Department of Radiology, University of Virginia Health System, Charlottesville, VA 22908, USA.

出版信息

Tech Vasc Interv Radiol. 2013 Jun;16(2):152-7. doi: 10.1053/j.tvir.2013.02.006.

Abstract

Since the conception of balloon-occluded retrograde transvenous obliteration (BRTO) of gastric varices 25 years ago, the placement of an indwelling balloon for hours has been central to the BRTO procedure. Numerous variables and variations of the BRTO procedure have been described, including methods to reduce sclerosant, combining percutaneous transhepatic obliteration, varying sclerosant, and using multiple sclerosants within the same procedure. However, the consistent feature of BRTO has always remained the indwelling balloon. Placing an indwelling balloon over hours for the BRTO procedure is a logistical burden that taxes the interventional radiology team and hospital resources. Substituting the balloon with hardware (coils or Amplatzer vascular plugs [AVPs] or both) is technically feasible and its risks most likely correlate with gastrorenal shunt (GRS) size. The current authors use packed 0.018- or 0.035-in coils or both for small gastric variceal systems (GRS size A and B) and AVPs for GRS sizes up to size E (from size A-E). The current authors recommend an indwelling balloon (no hardware substitute) for very large gastric variceal system (GRS size F). Substituting the indwelling balloon for hardware in size F and potentially size E GRS can also be risky. The current article describes the techniques of placing up to 16-mm AVPs through balloon occlusion guide catheters and then deflating the balloon once it has been substituted with the AVPs. In addition, 22-mm AVPs can be placed through sheaths once the balloon occlusion catheters are removed to further augment the 16-mm Amplatzer occlusion. To date, there are no studies describing, let alone evaluating, the clinical feasibility of performing BRTO without indwelling balloons. The described techniques have been successfully performed by the current authors. However, the long-term safety and effectiveness of these techniques is yet to be determined.

摘要

自25年前提出胃静脉曲张球囊闭塞逆行静脉闭塞术(BRTO)以来,留置球囊数小时一直是BRTO手术的核心操作。BRTO手术已有众多变量和变体被描述,包括减少硬化剂用量的方法、联合经皮经肝闭塞术、改变硬化剂以及在同一手术中使用多种硬化剂。然而,BRTO始终不变的特征是留置球囊。在BRTO手术中长时间放置留置球囊是一项后勤负担,对介入放射学团队和医院资源都造成了压力。用硬件(线圈或Amplatzer血管封堵器[AVP]或两者)替代球囊在技术上是可行的,其风险很可能与胃肾分流(GRS)大小相关。本文作者对于小型胃静脉曲张系统(GRS大小为A和B)使用填充的0.018英寸或0.035英寸线圈或两者,对于GRS大小达E(从A到E)的情况使用AVP。本文作者建议对于非常大的胃静脉曲张系统(GRS大小为F)使用留置球囊(不使用硬件替代)。在F型以及可能的E型GRS中用硬件替代留置球囊也可能有风险。本文描述了通过球囊闭塞引导导管放置最大16毫米AVP,然后在用AVP替代球囊后将球囊放气的技术。此外,在移除球囊闭塞导管后,可通过鞘管放置22毫米AVP以进一步增强16毫米Amplatzer封堵效果。迄今为止,尚无研究描述更不用说评估不使用留置球囊进行BRTO的临床可行性。本文作者已成功实施了所描述的技术。然而,这些技术的长期安全性和有效性尚待确定。

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