Sokol S, Jacobson C B, Derrick F C
Urology. 1975 Jul;6(1):59-62. doi: 10.1016/0090-4295(75)90594-4.
In sperm-freezing for infertility patients with low sperm counts, we found that semen containing high numbers of white blood cells, greater than 15 to 20 per high-power field, was both poor in quality and difficult to freeze. In examining these patients carefully, we found that many had smoldering prostatitis and some an overt history of prostatitis. We treated them with methenamine hippurate using various methods and found that by decreasing the white blood cell count in their semen, we could frequently improve the semen quality, particularly sperm motility, also achieve pregnancies in some cases.
在为精子数量少的不育症患者进行精子冷冻时，我们发现，每高倍视野白细胞数量超过15至20个的精液质量较差且难以冷冻。在仔细检查这些患者时，我们发现许多人患有隐匿性前列腺炎，有些人有明显的前列腺炎病史。我们用多种方法使用马尿酸乌洛托品对他们进行治疗，发现通过降低他们精液中的白细胞数量，我们常常可以改善精液质量，尤其是精子活力，在某些情况下还能实现受孕。
