Weidner W, Krause W, Schiefer H G, Brunner H, Friedrich H J
Urol Int. 1985;40(1):5-9. doi: 10.1159/000281023.
Ureaplasma urealyticum is considered an etiologic agent in urogenital tract infections, especially prostatitis. Using the 'four-specimen technique', diagnosis can be based upon significant numbers of these microorganisms. In ejaculate, the critical number seems to be 10(3) cfu/ml of semen to discriminate between real infection and contamination during urethral passage. In our study, 46 of 412 samples (11.2%) exceeded this critical number. Most but not all patients suffering from ureaplasma-associated prostatitis established by the 'four-specimen technique' revealed significantly high ejaculate numbers, whereas all samples from patients with prostatodynia and healthy controls had lower numbers. In these cases, numbers of round cells in semen, i.e. all leukocytes and spermatides, were significantly increased as compared to prostatodynia. A significantly negative correlation was detected between the numbers of ureaplasmas and zinc concentration in semen, and an almost identically negative correlation to the content of fructose, thus indicating secretory dysfunction of the accessory glands in ureaplasmal infections of the prostate.
解脲脲原体被认为是泌尿生殖道感染尤其是前列腺炎的病原体。采用“四标本技术”，可根据这些微生物的大量存在进行诊断。在精液中，关键数量似乎是每毫升精液10³ 菌落形成单位，以区分尿道排出过程中的真正感染和污染。在我们的研究中，412份样本中有46份（11.2%）超过了这个关键数量。大多数但并非所有通过“四标本技术”确诊为脲原体相关性前列腺炎的患者精液数量显著偏高，而所有来自前列腺痛患者和健康对照者的样本数量较低。在这些病例中，与前列腺痛患者相比，精液中的圆形细胞数量（即所有白细胞和精子细胞）显著增加。检测到精液中脲原体数量与锌浓度之间存在显著负相关，与果糖含量也几乎呈相同的负相关，这表明前列腺脲原体感染时附属腺体存在分泌功能障碍。
