Department of Chemical and Biomolecular Engineering, Korea Advanced Institute of Science and Technology, Daejeon 305-701, Korea.
Adv Healthc Mater. 2014 Jan;3(1):36-41. doi: 10.1002/adhm.201300100. Epub 2013 Jul 5.
Nanocomposite to achieve ultrafast immunoassay: a new synergistically integrated nanocomposite consisting of magnetic and platinum nanoparticles, simultaneously entrapped in mesoporous carbon, is developed as a promising enzyme mimetic candidate to achieve ultrafast colorimetric immunoassays. Using new assay system, clinically important target molecules, such as human epidermal growth factor receptor 2 (HER2) and diarrhea-causing rotavirus, can be detected in only 3 min at room temperature with high specificity and sensitivity.
开发了一种新型协同集成的纳米复合材料，由磁性和铂纳米粒子同时包埋在介孔碳中，作为一种有前途的酶模拟物候选物，可实现超快速比色免疫分析。使用新的分析系统，在室温下仅需 3 分钟即可高特异性和高灵敏度地检测到临床重要的靶标分子，如人表皮生长因子受体 2（HER2）和引起腹泻的轮状病毒。
