Department of Urology, The Second Xiangya Hospital, Central South University, 139 Middle Renmin Road, Changsha 410011, Hunan, China.
Hong Kong Med J. 2013 Aug;19(4):341-8. doi: 10.12809/hkmj134013. Epub 2013 Jul 8.
Ketamine is a relatively new recreational drug used by youngsters in recent decades. Its toxic effects on the genitourinary system were first reported in 2007, and now attract extensive attention from urologists, pharmacologists, and toxicologists all over the world. As many front-line health professionals and medical social workers are still unaware of this new clinical entity and an increasing number of the drug users seek help for urological symptoms, this mini-review aimed to summarise the clinical features and possible mechanisms of ketamine-induced genitourinary toxicity. By raising public awareness of these toxic effects, the authors hope that the contents of this review will be widely disseminated not only to medical professionals, but also to relevant government departments and the general public.
氯胺酮是近几十年来年轻人中使用的一种相对较新的消遣性药物。2007 年首次报道了其对泌尿生殖系统的毒性作用，现在引起了全世界泌尿科医生、药理学家和毒理学家的广泛关注。由于许多一线卫生专业人员和医务社会工作者仍然不知道这种新的临床实体，并且越来越多的药物使用者因泌尿系统症状寻求帮助，因此本篇小型综述旨在总结氯胺酮引起的泌尿生殖系统毒性的临床特征和可能的机制。通过提高公众对这些毒性作用的认识，作者希望本综述的内容不仅能广泛传播给医疗专业人员，也能传播给相关政府部门和公众。
