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涂片阳性肺结核患者的诊断延误

Diagnosis delay in smear positive tuberculosis patients.

作者信息

Nasehi Mahshid, Hassanzadeh Jafar, Rezaianzadeh Abbas, Zeigami Bahram, Tabatabaee Hamidreza, Ghaderi Ebrahim

机构信息

Epidemiology and Biostatistics Department, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.

出版信息

J Res Med Sci. 2012 Nov;17(11):1001-4.

Abstract

BACKGROUND

Early diagnosis of tuberculosis (TB) is a major key for effective TB program. Evaluation of delay in diagnosis of smear positive TB is needed to evaluation of TB program situation in each country. The aim of this study was to evaluate of diagnosis delay in smear positive tuberculosis patients in Islamic Republic of Iran.

MATERIALS AND METHODS

In this cross sectional study, all smear positive TB registered patients from 20 March 2009 to 20 March 2010 in Iran were assessed. Diagnosis delay is defined as the time interval between the first presentations of TB symptoms to the TB confirmation. Mann-Whitney test, chi-square and logistic regression was used to analysis.

RESULTS

Diagnosis delay was 58 days in female and 53 days in male (P=0.004), 61 days in non-Iranian and 54 days in Iranian (P<0.001), 59 days in urban and 50 days in rural (P<0.001), 57 days in non-prisoner and 37 days in prisoner (P<0.001), 61 days in patients who chose private outpatients system and 52 days in patients who chose Public health outpatients system (P<0.001). 193 (9.4%) had 1-9 bacilli and 2132 (37.4%) were 3+ in sputum smear examination.

CONCLUSION

Non-Iranian, urban, non-prisoner, old patients and the patients who chose private system are in risk of delay diagnosis of TB. Cooperation of private system through public-private mix model is an important key in successful national TB program (NTP).

摘要

背景

结核病的早期诊断是有效结核病防治规划的关键。评估涂片阳性结核病诊断延迟情况对于评估各国结核病防治规划状况很有必要。本研究旨在评估伊朗伊斯兰共和国涂片阳性结核病患者的诊断延迟情况。

材料与方法

在这项横断面研究中,对2009年3月20日至2010年3月20日期间伊朗所有登记的涂片阳性结核病患者进行了评估。诊断延迟定义为从首次出现结核病症状到确诊结核病之间的时间间隔。采用曼-惠特尼检验、卡方检验和逻辑回归进行分析。

结果

女性的诊断延迟为58天,男性为53天(P = 0.004);非伊朗人的诊断延迟为61天,伊朗人为54天(P < 0.001);城市地区为59天,农村地区为50天(P < 0.001);非囚犯为57天,囚犯为37天(P < 0.001);选择私立门诊系统的患者为61天,选择公共卫生门诊系统的患者为52天(P < 0.001)。在痰涂片检查中,193例(9.4%)有1 - 9条杆菌,2132例(37.4%)为3+。

结论

非伊朗人、城市居民、非囚犯、老年患者以及选择私立系统的患者有结核病诊断延迟的风险。通过公私混合模式使私立系统参与合作是国家结核病防治规划成功实施的关键。

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