Woo Kevin Y, Keast David, Parsons Nancy, Sibbald R Gary, Mittmann Nicole
School of Nursing, Queen's University, Kingston, Ontario, Canada.
Aging, Rehabilitation and Geriatric Care Research Centre, St. Joseph's Parkwood Hospital, London, Ontario, Canada.
Int Wound J. 2015 Aug;12(4):402-7. doi: 10.1111/iwj.12122. Epub 2013 Jul 9.
Debridement is integral to wound bed preparation by removing devitalised tissue, foreign material, senescent cells, phenotypically abnormal/dysfunctional cells (cellular burden) and bacteria sequestrum (biofilm). While the body of evidence to substantiate the benefits of debridement is growing, little is known about the cost-effectiveness of each debridement method. The purpose of this analysis was to compare cost-effectiveness of various debridement methods and clinical outcomes to help inform clinicians and policy makers of the cost-effectiveness associated with the various types of therapies and the impact they can have on the Canadian health care system. Results indicated that sharp debridement was the most cost-effective followed by enzymatic debridement method.
清创术对于伤口床准备至关重要，它能清除失活组织、异物、衰老细胞、表型异常/功能失调的细胞（细胞负荷）以及细菌聚集体（生物膜）。虽然证实清创术益处的证据越来越多，但对于每种清创术方法的成本效益却知之甚少。本分析的目的是比较各种清创术方法的成本效益和临床结果，以帮助临床医生和政策制定者了解不同类型治疗方法的成本效益以及它们对加拿大医疗保健系统可能产生的影响。结果表明，锐性清创术是最具成本效益的，其次是酶促清创术。
