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首例免疫功能正常患者由土曲霉引起的皮下暗色丝孢霉病报告。

First report of subcutaneous phaeohyphomycosis caused by Ochroconis tshawytschae in an immunocompetent patient.

机构信息

Department of Mycology, Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College, Nanjing, People's Republic of China.

出版信息

Med Mycol. 2012 Aug;50(6):637-40. doi: 10.3109/13693786.2011.653834. Epub 2012 Feb 6.

DOI:10.3109/13693786.2011.653834
PMID:22309240
Abstract

We report the first case and clinical course of a case of human subcutaneous phaeohyphomycosis caused by Ochroconis tshawytschae, a rare fish pathogen. The diagnosis was based upon histopathological and mycological examinations of clinical samples. Identification of the etiologic agent was assessed on its phenotypic characteristics and subsequently, confirmed by molecular data. In vitro antifungal susceptibility of the isolate was investigated and a comparison was prepared of all of its features to those of its two most relevant related species, O. gallopava and O. humicola.

摘要

我们报告了首例由褐曲霉引起的人类皮下暗色丝孢霉病的病例和临床经过,褐曲霉是一种罕见的鱼类病原体。该诊断基于临床样本的组织病理学和真菌学检查。根据表型特征评估了病原体的鉴定,并随后通过分子数据进行了确认。对分离株的体外抗真菌药敏性进行了研究,并将其所有特征与两个最相关的近缘种,O. gallopava 和 O. humicola 进行了比较。

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