Pöltner Gustav, Miller Klaus, Berke Andreas, Sickenberger Wolfgang
Contactlinseninstitut Miller, Innsbruck, Austria.
Coll Antropol. 2013 Apr;37 Suppl 1:165-73.
To measure the corneal thickness and the depth of the precorneal tear film of contact lens wearers with keratoconus or keratoplasty and to reconfirm the identification and classification of the keratoconus with optical coherence tomography (OCT). The cornea and precorneal tear film of 123 eyes with keratoconus, of 39 eyes after keratoplasty and 8 eyes after LASIK were examined with an OCT (Zeiss Visante) and a keratograph (Oculus). Visual acuity was determined. The mean age of all patients was 42.7 years (sigma = 9). There were 35% female patients and 65% were male patients. The central corneal thickness of 123 eyes with keratoconus was 467 +/- 73 microm. The nasal and especially the inferior corneal periphery exhibit a 9% lesser thickness (426 +/- 83 microm). The cornea with keratoconus is thinner in the 90 degrees meridian, than in the 180 degrees meridian (p < 0.01). This could be a clinically relevant result for the reduction of astigmatism after keratoplastic surgery. The central corneal thickness of 39 eyes with keratoplasty was 555 +/- 65 microm. These eyes showed peripheral parts with even less thickness. The thickness of the precorneal tear film of 114 contact lens wearers with keratoconus was 89 +/- 42 microm in the horizontal meridian, 113 +/- 56 microm in the vertical meridian. All the comparative results in case of keratoconus, keratoplasty and the depth of the precorneal tear film had high statistical significance (p < 0.001). Optical coherence tomography is particularly suitable for the examination of eyes with keratoconus and keratoplasty. It delivers new insight into corneal thickness of eyes with keratoconus and keratoplasty.
测量圆锥角膜或角膜移植术后隐形眼镜佩戴者的角膜厚度和角膜前泪膜深度，并用光学相干断层扫描（OCT）重新确认圆锥角膜的识别和分类。使用OCT（蔡司Visante）和角膜地形图仪（欧科路斯）检查了123只圆锥角膜眼、39只角膜移植术后眼和8只准分子激光原位角膜磨镶术（LASIK）术后眼的角膜和角膜前泪膜。测定了视力。所有患者的平均年龄为42.7岁（标准差=9）。女性患者占35%，男性患者占65%。123只圆锥角膜眼的中央角膜厚度为467±73微米。鼻侧尤其是角膜下周边厚度薄9%（426±83微米）。圆锥角膜在90度子午线处比在180度子午线处更薄（p<0.01）。这可能是角膜移植手术后散光减少的一个临床相关结果。39只角膜移植术后眼的中央角膜厚度为555±65微米。这些眼睛的周边部分厚度更薄。114名圆锥角膜隐形眼镜佩戴者角膜前泪膜的厚度在水平子午线为89±42微米，在垂直子午线为113±56微米。圆锥角膜、角膜移植术以及角膜前泪膜深度的所有比较结果均具有高度统计学意义（p<0.001）。光学相干断层扫描特别适用于圆锥角膜和角膜移植术后眼的检查。它为圆锥角膜和角膜移植术后眼的角膜厚度提供了新的见解。
