Skene A I, Bulman A S, Williams T R, Thomas J M, Westbury G
Department of Academic Surgery, Royal Marsden Hospital, London, UK.
Br J Surg. 1990 Jul;77(7):765-7. doi: 10.1002/bjs.1800770716.
A retrospective study of 91 patients with malignant melanoma treated by lower limb isolated hyperthermic regional perfusion was performed. Objective response in patients with evaluable disease was 78 per cent. The role of perfusion as primary treatment of large melanomas of the foot is confirmed and recommended. Control of locoregional disease and limb salvage remains a valuable and attainable therapeutic goal using this technique.
对91例接受下肢孤立性热灌注治疗的恶性黑色素瘤患者进行了回顾性研究。可评估疾病患者的客观缓解率为78%。证实并推荐灌注作为足部大型黑色素瘤的主要治疗方法。使用该技术控制局部区域疾病和保肢仍然是一个有价值且可实现的治疗目标。
