Martinot A, Cohen R, Denis F, Gaudelus J, Lery T, Le Danvic M, Stahl J-P
EA 2694, clinique de pédiatrie, CHU de Lille, université Lille Nord de France, 2, avenue Oscar-Lambret, 59037 Lille, France.
Arch Pediatr. 2013 Aug;20(8):837-44. doi: 10.1016/j.arcped.2013.05.016. Epub 2013 Jul 6.
Assessing vaccination coverage (VC) is a critical part of adherence to immunization guidelines and beyond vaccine effectiveness can fill possible gaps and optimize VC. The aim of this study was to measure annual VC trends (2008-2011) among children 0-6years of age.
An Internet survey was conducted using a self-administrated questionnaire to a representative sample (quota method) of mothers reporting their child's immunization record.
Diphtheria-tetanus-poliomyelitis-pertussis VC (complete schedule) was 96.0% at 6 years of age in 2010. Hepatitis B VC (≥1 dose) in the 6- to 11-month-old population increased from 54.6% in 2008 to 80.5% in 2011, but only 34.7% of 6-year-old had received a complete schedule in 2010. Pneumococcal conjugate vaccine VC (complete schedule) increased to 92.7% in the 24- to 35-month-old population. Measles-mumps-rubella (MMR) VC (2 injections) increased in 24- to 35-month-olds from 60.3% in 2008 to 81.0% in 2011. In 2011, 64.2% of 24- to 35-month-olds had received a second dose of MMR vaccine before 25 months vs. 45.4% in 2008. BCG VC in 12- to 35-month-olds was 73.2% in Île-de-France, where vaccination is recommended in all children vs. 15.5% elsewhere (vaccination only recommended in high-risk children).
This study shows a significant improvement of VC in young French children. However, outreach efforts should continue to be made, especially to adolescent and adult populations, in whom VC is very low.
评估疫苗接种覆盖率（VC）是遵守免疫指南的关键部分，除疫苗有效性外，还可以填补可能存在的差距并优化疫苗接种覆盖率。本研究的目的是测量0至6岁儿童的年度疫苗接种覆盖率趋势（2008 - 2011年）。
通过互联网调查，使用自我管理问卷对报告其孩子免疫记录的母亲进行代表性抽样（配额法）。
2010年，6岁儿童白喉 - 破伤风 - 脊髓灰质炎 - 百日咳疫苗接种覆盖率（完整接种程序）为96.0%。6至11个月大人群的乙肝疫苗接种覆盖率（≥1剂）从2008年的54.6%增至2011年的80.5%，但2010年只有34.7%的6岁儿童完成了完整接种程序。24至35个月大人群的肺炎球菌结合疫苗接种覆盖率（完整接种程序）增至92.7%。24至35个月大儿童的麻疹 - 腮腺炎 - 风疹（MMR）疫苗接种覆盖率（2剂）从2008年的60.3%增至2011年的81.0%。2011年，24至35个月大儿童中有64.2%在25个月前接种了第二剂MMR疫苗，而2008年为45.4%。在法兰西岛，12至35个月大儿童的卡介苗接种覆盖率为73.2%，该地区建议所有儿童接种疫苗，而其他地区为15.5%（仅建议高危儿童接种）。
本研究表明法国幼儿的疫苗接种覆盖率有显著提高。然而，仍应继续开展推广工作，特别是针对疫苗接种覆盖率非常低的青少年和成人人群。
