Croucher Institute for Environmental Sciences, and Department of Biology, Hong Kong Baptist University, Hong Kong, PR China.
Environ Int. 2013 Sep;59:208-24. doi: 10.1016/j.envint.2013.06.012. Epub 2013 Jul 6.
Pharmaceuticals and personal care products (PPCPs) which contain diverse organic groups, such as antibiotics, hormones, antimicrobial agents, synthetic musks, etc., have raised significant concerns in recently years for their persistent input and potential threat to ecological environment and human health. China is a large country with high production and consumption of PPCPs for its economic development and population growth in recent years. This may result in PPCP contamination in different environmental media of China. This review summarizes the current contamination status of different environment media, including sewage, surface water, sludge, sediments, soil, and wild animals, in China by PPCPs. The human body burden and adverse effects derived from PPCPs are also evaluated. Based on this review, it has been concluded that more contamination information of aquatic environment and wildlife as well as human body burden of PPCPs in different areas of China is urgent. Studies about their environmental behavior and control technologies need to be conducted, and acute and chronic toxicities of different PPCP groups should be investigated for assessing their potential ecological and health risks.
药品和个人护理产品(PPCPs)含有多种有机基团,如抗生素、激素、抗菌剂、合成麝香等,近年来因其持续输入和对生态环境和人类健康的潜在威胁而引起了极大关注。中国是一个生产和消费 PPCPs 大国,近年来经济发展和人口增长,这可能导致中国不同环境介质中 PPCP 的污染。本综述总结了目前中国不同环境介质(污水、地表水、污泥、沉积物、土壤和野生动物)中 PPCPs 的污染状况。还评估了源自 PPCPs 的人体负担和不良影响。基于本综述,我们得出结论,中国不同地区需要更多有关水生环境和野生动物的污染信息以及 PPCPs 的人体负担,需要开展关于它们的环境行为和控制技术的研究,并调查不同 PPCP 组的急性和慢性毒性,以评估其潜在的生态和健康风险。