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线性免疫球蛋白 A 大疱性皮肤病:诊断标准需要达成一致。

Linear immunoglobulin a bullous dermatosis: need for an agreement on diagnostic criteria.

机构信息

Department of Medical and Surgical Critical Care, Section of Dermatology, University of Florence, Florence, Italy.

出版信息

Dermatology. 2013;226(4):329-32. doi: 10.1159/000350818. Epub 2013 Jul 3.

Abstract

Linear immunoglobulin A bullous dermatosis (LABD) is a rare, heterogeneous, autoimmune blistering disorder. Although the main characteristics of the disease seem to be well identified, international accepted diagnostic criteria are lacking. Several authors suggested their own criteria, but they are often not complete or even in contrast with clinical and immunopathological findings from the literature, while others are too selective. In this review, the current views and the problems with the definition of reliable diagnostic criteria for LABD will be discussed.

摘要

线性 IgA 大疱性皮病(LABD)是一种罕见的、异质性的自身免疫性大疱性疾病。尽管该病的主要特征似乎已经得到很好的确定,但仍缺乏国际公认的诊断标准。一些作者提出了自己的标准,但它们往往不完整,甚至与文献中的临床和免疫病理学发现相矛盾,而其他标准则过于选择性。在这篇综述中,将讨论目前对 LABD 可靠诊断标准的定义的观点和问题。

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