Department of General Surgery, Hotel Dieu de France Hospital, Faculty of Medicine, Saint-Joseph University, Beirut 6830, Lebanon.
World J Gastroenterol. 2013 Jul 7;19(25):3942-50. doi: 10.3748/wjg.v19.i25.3942.
At present, the treatment of choice for uncomplicated acute appendicitis in adults continues to be surgical. The inflammation in acute appendicitis may sometimes be enclosed by the patient's own defense mechanisms, by the formation of an inflammatory phlegmon or a circumscribed abscess. The management of these patients is controversial. Immediate appendectomy may be technically demanding. The exploration often ends up in an ileocecal resection or a right-sided hemicolectomy. Recently, the conditions for conservative management of these patients have changed due to the development of computed tomography and ultrasound, which has improved the diagnosis of enclosed inflammation and made drainage of intra-abdominal abscesses easier. New efficient antibiotics have also given new opportunities for nonsurgical treatment of complicated appendicitis. The traditional management of these patients is nonsurgical treatment followed by interval appendectomy to prevent recurrence. The need for interval appendectomy after successful nonsurgical treatment has recently been questioned because the risk of recurrence is relatively small. After successful nonsurgical treatment of an appendiceal mass, the true diagnosis is uncertain in some cases and an underlying diagnosis of cancer or Crohn's disease may be delayed. This report aims at reviewing the treatment options of patients with enclosed appendiceal inflammation, with emphasis on the success rate of nonsurgical treatment, the need for drainage of abscesses, the risk of undetected serious disease, and the need for interval appendectomy to prevent recurrence.
目前,成人单纯性急性阑尾炎的治疗选择仍然是手术。急性阑尾炎的炎症有时可能被患者自身的防御机制所包围,形成炎性痰或局限性脓肿。这些患者的治疗存在争议。立即进行阑尾切除术可能在技术上具有挑战性。探查往往最终导致回盲部切除术或右侧结肠切除术。最近,由于计算机断层扫描和超声技术的发展,这些患者的保守治疗条件发生了变化,这提高了封闭性炎症的诊断水平,并使腹腔脓肿的引流变得更加容易。新的高效抗生素也为复杂阑尾炎的非手术治疗提供了新的机会。这些患者的传统治疗方法是先进行非手术治疗,然后再进行间隔性阑尾切除术以预防复发。最近,人们对成功进行非手术治疗后是否需要间隔性阑尾切除术提出了质疑,因为复发的风险相对较小。在成功进行阑尾包块的非手术治疗后,某些情况下真正的诊断仍不确定,可能会延迟诊断出潜在的癌症或克罗恩病。本报告旨在回顾封闭性阑尾炎症患者的治疗选择,重点介绍非手术治疗的成功率、脓肿引流的必要性、未发现严重疾病的风险以及为预防复发而进行间隔性阑尾切除术的必要性。