Iqbal Nida, Sharma Atul
Department of Medical Oncology, Dr. B. R. A. Institute Rotary Cancer Hospital, All India Institute of Medical Sciences, New Delhi 110029, India.
Case Rep Oncol Med. 2013;2013:109412. doi: 10.1155/2013/109412. Epub 2013 Jun 13.
Malignancy is known to be one of the predisposing factors of cerebral venous thrombosis (CVT) due to its hypercoagulable state. CVT is a rare disorder which can lead to frequent misdiagnoses of brain metastases in such cases. We report here the case of a 35-year-old female with metastatic colon adenocarcinoma presenting with sudden neurological symptoms. Brain MRI and magnetic resonance venography confirmed the presence of CVT. She was treated with low molecular weight heparin followed by warfarin. She recovered and is doing well on warfarin after 5 months of diagnosis of CVT. CVT should be strongly suspected as a cause of neurological dysfunction in any case of disseminated malignancy including colon adenocarcinoma. Rapid diagnosis and initiation of therapy should be considered because of its favourable outcome.
由于恶性肿瘤处于高凝状态，它被认为是脑静脉血栓形成（CVT）的诱发因素之一。CVT是一种罕见的疾病，在这种情况下常导致脑转移瘤的误诊。我们在此报告一例35岁女性转移性结肠腺癌患者，其出现突发神经症状。脑部MRI和磁共振静脉造影证实存在CVT。她接受了低分子量肝素治疗，随后使用华法林。在诊断CVT 5个月后，她康复且服用华法林情况良好。在任何播散性恶性肿瘤（包括结肠腺癌）病例中，都应高度怀疑CVT是神经功能障碍的原因。鉴于其良好的预后，应考虑快速诊断并开始治疗。
