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臂丛神经硬纤维瘤

Desmoid tumour of the brachial plexus.

作者信息

Juliette Orege, Florentius Koech, Francis Ndiangui, Macharia Benson Ndegwa, Neema Mbaruku

机构信息

Department of Radiology, Moi University School of Medicine, P.O. Box 4606, Eldoret 30100, Kenya.

出版信息

Case Rep Surg. 2013;2013:575982. doi: 10.1155/2013/575982. Epub 2013 Jun 12.

Abstract

Desmoid tumours of the brachial plexus are rare and may occur in extra-abdominal sites. The tumours are of fibroblastic origin and, although benign, are locally aggressive. Their relationship to critical neurovascular structures in their anatomic locations presents a challenge to the operating surgeons trying to adhere to the principles of surgery. Surprisingly little neurosurgical literature exists which was devoted to this topic despite the challenge these lesions present in surgery both at surgery and in choosing adjuvant therapies. We report a case of a large brachial plexus tumour in a patient which was diagnosed radiologically and histopathologically and the patient underwent surgical excision with good outcome. Desmoid tumours histologically are benign and are usually composed of proliferating, benign fibroblasts in an abundant matrix of collagen. They do not transform into malignant tumours or metastasize. Surgery is the mainstay of treatment; however, adjuvant radiation and chemotherapy remain controversial.

摘要

臂丛神经硬纤维瘤罕见,可发生于腹外部位。这些肿瘤起源于成纤维细胞,虽为良性,但具有局部侵袭性。它们在解剖位置上与关键神经血管结构的关系,给试图遵循手术原则的外科医生带来了挑战。尽管这些病变在手术及选择辅助治疗方面都存在挑战,但令人惊讶的是,专门针对该主题的神经外科文献却很少。我们报告一例患者的大型臂丛神经肿瘤,该肿瘤经放射学和组织病理学诊断,患者接受了手术切除,效果良好。硬纤维瘤在组织学上为良性,通常由在丰富胶原基质中增殖的良性成纤维细胞组成。它们不会转变为恶性肿瘤或发生转移。手术是主要的治疗方法;然而,辅助放疗和化疗仍存在争议。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9fa0/3694380/2e82f57d4673/CRIM.SURGERY2013-575982.001.jpg

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