影响健康婴儿生命最初 48 小时内胆红素水平的因素。
Factors affecting bilirubin levels during first 48 hours of life in healthy infants.
机构信息
Division of Neonatology, Department of Pediatrics, Ege University Faculty of Medicine, Izmir, Turkey.
出版信息
Biomed Res Int. 2013;2013:316430. doi: 10.1155/2013/316430. Epub 2013 Jun 6.
OBJECTIVE
To investigate the relationship of delivery type, maternal anesthesia, feeding modalities, and first feeding and meconium passage times with early bilirubin levels of healthy infants.
METHODS
Cord, 24 hours' and 48 hours' total bilirubin levels were measured in 388 study infants.
RESULTS
Infants born with cesarean section were fed later and more often had mixed feeding. First meconium passage was delayed with general anesthesia. Cord, 24 and 48 hours' bilirubin levels were not correlated with first feeding time, meconium passage time, mode of delivery, existence and type of anesthesia, and feeding modalities. Being in high intermediate risk zone at 72 hours of Bhutani's nomogram was only related to first feeding time and high cord bilirubin level. Late preterm infants were more frequently born with cesarean section and offered supplementary formula. Therefore, first meconium passage times and bilirubin levels were similar in the late preterm and term infants.
CONCLUSIONS
Type of delivery or anesthesia, late prematurity, feeding modalities, and first meconium passage time were not related to early bilirubin levels in healthy neonates, but delayed first feeding and high cord bilirubin levels were related to be in higher risk zone for later hyperbilirubinemia.
目的
探讨健康婴儿的分娩方式、产妇麻醉、喂养方式以及首次喂养和胎便排出时间与早期胆红素水平的关系。
方法
对 388 例研究婴儿的脐带、24 小时和 48 小时总胆红素水平进行了测量。
结果
剖宫产出生的婴儿喂养较晚，混合喂养更为常见。全身麻醉会延迟首次胎便排出。脐带、24 小时和 48 小时胆红素水平与首次喂养时间、胎便排出时间、分娩方式、麻醉的存在和类型以及喂养方式均无相关性。在布塔尼氏命名法的 72 小时高危区中，仅与首次喂养时间和高脐带胆红素水平有关。晚期早产儿更常行剖宫产分娩，并补充配方奶。因此，晚期早产儿和足月儿的首次胎便排出时间和胆红素水平相似。
结论
分娩方式或麻醉方式、晚期早产儿、喂养方式以及首次胎便排出时间与健康新生儿的早期胆红素水平无关，但首次喂养延迟和高脐带胆红素水平与后期高胆红素血症的高风险区有关。
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