Su Hai-Xia, Zhang Zhao-Hui, Zhao Xiao-Yan, Li Zhi, Yan Fang, Zhang Han
Department of Instrumentation Science, University of Science & Technology Beijing, Beijing 100083, China.
Guang Pu Xue Yu Guang Pu Fen Xi. 2013 Apr;33(4):921-5.
Using THz-TDS to detect the THz temporal pulse and calculate the absorption spectrum of the sample is the main access to qualitative and quantitative analysis. The shape and the amplitude of the THz absorption spectra are not only related to the sample, but also closely related to the length of the chosen THz pulse in the calculation, which was discovered in our experiments. It is the main cause of this problem that the flaky sample reflects the THz wave many times, which will give rise to the Fabry-Perot effect. So the sample-probing temporal signal is divided into the intrinsic section with the sample's information directly, low SNR noise section, and unwanted Fabry-Perot reflections section with the overlapped information. Based on THz pulse generation mechanism and the relationship between the pulse amplitude and the attenuate process, a model of intercepting the intrinsic section in terahertz time-domain pulse was proposed and was proved reliable and stable by the results from experiments performed with amino acids: glutamine(Gln), histidine(His), and cystine(Cys).
利用太赫兹时域光谱(THz-TDS)检测太赫兹时域脉冲并计算样品的吸收光谱是进行定性和定量分析的主要途径。太赫兹吸收光谱的形状和幅度不仅与样品有关,在我们的实验中还发现,在计算中它与所选太赫兹脉冲的长度也密切相关。片状样品多次反射太赫兹波是产生这个问题的主要原因,这会导致法布里-珀罗效应。所以,样品探测时域信号被分为直接包含样品信息的本征部分、低信噪比噪声部分以及包含重叠信息的不需要的法布里-珀罗反射部分。基于太赫兹脉冲产生机制以及脉冲幅度与衰减过程之间的关系,提出了一种在太赫兹时域脉冲中截取本征部分的模型,并且通过对氨基酸:谷氨酰胺(Gln)、组氨酸(His)和胱氨酸(Cys)进行的实验结果证明该模型可靠且稳定。