Calhoun Cardiology Center, University of Connecticut School of Medicine, Farmington, CT, USA.
Am J Drug Alcohol Abuse. 2013 Jul;39(4):266-71. doi: 10.3109/00952990.2013.803112.
Multiple types of substance use are associated with HIV risk behaviors, but relatively little research has examined the association between marijuana use and risky sexual activities in treatment-seeking polysubstance abusing patients.
This study evaluated the relationship between marijuana use and sexual behaviors in 239 patients with cocaine, opioid or alcohol use disorders who were initiating outpatient substance use treatment.
Participants completed the HIV Risk Behavior Scale and were classified into one of three groups based on their marijuana use histories: never (n = 66), past but not current use (n = 124) or current use (n = 49).
Compared to never marijuana users, current and former marijuana users had a greater likelihood of having more than 50 lifetime sexual partners (odds ratio [OR] and 95% confidence interval [CI] = 3.9 [1.0-15.7] and 5.2 [1.6-17.3], respectively). Former marijuana users had increased risk of low frequency condom use with casual partners relative to never users (OR [95% CI] = 2.9 [1.1-7.6]). Moreover, current marijuana users were more likely than never users to have had more than two recent sexual partners (OR [95% CI] = 8.1 [1.94-33.44]).
Treatment-seeking polysubstance abusers with current or past marijuana use histories may be at greater risk of HIV infection than their counterparts who do not use marijuana. These data underscore the importance of increasing awareness about the potential association between marijuana use and increased high-risk sexual behavior among polysubstance abusing patients.
多种物质使用与 HIV 风险行为相关,但相对较少的研究调查了在寻求治疗的多种物质滥用患者中,大麻使用与危险性行为之间的关系。
本研究评估了 239 名可卡因、阿片类药物或酒精使用障碍患者开始门诊物质使用治疗时,大麻使用与性行为之间的关系。
参与者完成了 HIV 风险行为量表,并根据他们的大麻使用史分为三组:从未使用(n=66)、过去但现在不使用(n=124)或现在使用(n=49)。
与从未使用大麻的人相比,现在和以前使用大麻的人有更多的可能性有超过 50 个性伴侣(优势比 [OR] 和 95%置信区间 [CI] = 3.9 [1.0-15.7] 和 5.2 [1.6-17.3])。与从未使用者相比,以前使用大麻的人更有可能与偶然伴侣发生低频率使用避孕套的情况(OR [95% CI] = 2.9 [1.1-7.6])。此外,现在使用大麻的人比从未使用者更有可能有两个以上的近期性伴侣(OR [95% CI] = 8.1 [1.94-33.44])。
目前或过去有大麻使用史的寻求治疗的多种物质滥用者可能比不使用大麻的人更容易感染 HIV。这些数据强调了提高对大麻使用与多种物质滥用患者增加高危性行为之间潜在关联的认识的重要性。