Pieters Toine, de Hon Olivier
Universiteit Utrecht, afd. Farmaco-epidemiologie en Klinische Farmacologie, Utrecht, the Netherlands.
Ned Tijdschr Geneeskd. 2013;157(28):A6450.
Physicians should possess specific diagnostic and pharmacotherapeutic skills in order to recognize symptoms associated with doping use. It is important to be on the alert in athletes and fitness enthusiasts for physical and psychological changes due to use of anabolic steroids such as acne, stretch marks, gynecomastia, signs of acromegaly, irascibility and lethargy. Stimulants such as amphetamines, ephedrine and cocaine lead to fat loss and increased alertness; their main side effects are cardiac problems, behavioural changes and addiction. In addition to anabolic steroids and stimulants, erythropoietin, growth hormone, diuretics and glucocorticoids are regularly used to improve sport performance. In cycling, a biological passport will be used in an attempt to detect doping use. In future, the Olympic motto 'citius, altius, fortius' (faster, higher, stronger) will have ground-breaking consequences for the performance and health of top athletes.
医生应具备特定的诊断和药物治疗技能,以便识别与使用兴奋剂相关的症状。对运动员和健身爱好者而言,警惕因使用合成代谢类固醇而导致的身体和心理变化非常重要,这些变化包括痤疮、妊娠纹、男性乳房发育、肢端肥大症迹象、易怒和嗜睡等。苯丙胺、麻黄碱和可卡因等兴奋剂会导致体重减轻和警觉性提高;其主要副作用是心脏问题、行为改变和成瘾。除了合成代谢类固醇和兴奋剂外,促红细胞生成素、生长激素、利尿剂和糖皮质激素也经常被用于提高运动成绩。在自行车运动中,将使用生物护照来试图检测兴奋剂的使用情况。未来,奥林匹克格言“更快、更高、更强”将对顶尖运动员的表现和健康产生开创性的影响。