Maier M M, Feucht N, Burzer S, Lohmann C P
Augenklinik, Klinikum rechts der Isar, Technische Universität München.
Klin Monbl Augenheilkd. 2013 Sep;230(9):920-8. doi: 10.1055/s-0032-1328641. Epub 2013 Jul 10.
In vitreomacular traction syndrome (VMTS) an anomalous posterior vitreous detachment (APVD) with persistant symptomatic vitreoretinal adhesion is seen. The adhesion leads to a thickened macula, to macular oedema and a reduction of BCVA. Modern imaging techniques like spectral domain OCT (SD-OCT) allow a detailed imaging of the retinal microstructure and the vitreoretinal interface. Vitreomacular adhesions and their effect on the retina can be visualised. Until now, the treatment option for VMTS was and is vitreoretinal surgery. In studies pharmacological vitreolysis has shown a therapeutic effect in patients with symptomatic adhesion and traction. The results of these studies represent an important step towards a pharmacological treatment of VMTS.
在玻璃体黄斑牵拉综合征（VMTS）中，可见伴有持续性症状性玻璃体视网膜粘连的异常玻璃体后脱离（APVD）。这种粘连会导致黄斑增厚、黄斑水肿以及最佳矫正视力（BCVA）下降。像光谱域光学相干断层扫描（SD - OCT）这样的现代成像技术能够对视网膜微观结构和玻璃体视网膜界面进行详细成像。玻璃体黄斑粘连及其对视网膜的影响可以可视化。到目前为止，VMTS的治疗选择一直是玻璃体视网膜手术。在研究中，药物性玻璃体溶解术已显示出对有症状粘连和牵拉的患者具有治疗效果。这些研究结果是VMTS药物治疗的重要一步。
