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[以色列孕妇的艾滋病毒筛查:根据当地流行病学对当前选择性筛查建议的评估]

[HIV screening for pregnant women in Israel: evaluation of current selective screening recommendations in the light of the local epidemiology].

作者信息

Mor Zohar, Pinsker Galia, Levy Chezi, Haddad Efrat, Levin Hagai, Grotto Itamar

机构信息

Department of TB and AIDS, Ministry of Health, Jerusalem, Israel.

出版信息

Harefuah. 2013 Apr;152(4):220-3, 246.

Abstract

INTRODUCTION

HIV-testing in Israel for pregnant women (PW) is selective since the year 1998 and recommended if they or their sex partners (SP] are at high-risk for HIV-infection. HIV-infected PW, citizens and non-citizens alike, are eligible for free HIV-care and treatment. This study describes the current recommendations and HIV epidemiology in Israel.

METHODS

A retrospective study was conducted describing risk groups of HIV-infected PW between the years 1985 and 2010. The source of the data was the National HIV registry.

RESULTS

During 25 years of follow-up, 204 vertically HIV-infected children were reported to the Ministry of Health (MoH). Of those, 87 (42.4%) were born in Israel to 83 PW, and the others were born overseas. Of these 87 children, 35 (40.2%) were born to 33 PWwho were unaware of their HIV-infection prior to Labor (31 citizens and 2 non-citizens). Of those, 22 (66.7%) were born in high-prevalence countries, eight (24.3%) were infected from their heterosexual SP, one (3%) used drugs intravenously, one (3%) had a SPwho used drugs intravenously, and one (3%) had a SP who received HIV-infected blood. During the period 2002-2011, the treatment costs of 54 non-citizens PW was covered by the MoH and no vertical infection was diagnosed.

CONCLUSIONS

Most vertical transmissions occurred overseas, or by PW who were aware of their infection prior to Labor. Most of the PW who were unaware of their HIV-infection and gave birth in Israel belonged to the known risk groups for whom testing is recommended. SeLective HIV-testing in these PW should be encouraged, along with a vigilant surveiLLance of new HIV-infections in women.

摘要

引言

自1998年起,以色列针对孕妇的艾滋病毒检测是选择性的,若孕妇本人或其性伴侣有感染艾滋病毒的高风险,则建议进行检测。感染艾滋病毒的孕妇,无论其是公民还是非公民,均有资格获得免费的艾滋病毒护理和治疗。本研究描述了以色列当前的相关建议及艾滋病毒流行病学情况。

方法

开展一项回顾性研究,描述1985年至2010年间感染艾滋病毒的孕妇的风险群体。数据来源为国家艾滋病毒登记处。

结果

在25年的随访期间,向卫生部报告了204例垂直感染艾滋病毒的儿童。其中,87例(42.4%)在以色列出生,其母亲为83名孕妇,其余在海外出生。在这87名儿童中,35例(40.2%)的母亲为33名在分娩前不知自己感染艾滋病毒的孕妇(31名公民和2名非公民)。其中,22例(66.7%)在高流行国家出生,8例(24.3%)通过异性性伴侣感染,1例(3%)静脉吸毒,1例(3%)性伴侣静脉吸毒,1例(3%)性伴侣接受过艾滋病毒感染血液。2002年至2011年期间,卫生部承担了54名非公民孕妇的治疗费用,未诊断出垂直感染病例。

结论

大多数垂直传播发生在海外,或由分娩前已知感染的孕妇传播。大多数在以色列分娩但不知自己感染艾滋病毒的孕妇属于建议进行检测的已知风险群体。应鼓励对这些孕妇进行选择性艾滋病毒检测,并对女性中的新艾滋病毒感染情况进行警惕监测。

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