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缺血性心脏病患者一级亲属的血清胆固醇结合储备及其与血清胆固醇的比值。

Serum cholesterol binding reserve and its ratio to serum cholesterol in first degree relatives of patients with ischaemic heart disease.

作者信息

Goyal S P, Singh R, Wahal P K, Jain V K, Pursnani M L, Singh M M, Sodhi B S

机构信息

PG Dep of Medicine, Medical College, Agra.

出版信息

J Assoc Physicians India. 1990 Jun;38(6):395-7.

PMID:2384453
Abstract

Serum total cholesterol and serum cholesterol binding reserve (SCBR) were estimated in 50 healthy subjects and 25 cases with ischaemic heart disease (IHD) and their seventy asymptomatic first degree relatives. In normal subjects mean values of SCBR tended to expand with increasing levels of serum cholesterol, while this relationship was reversed in cases with IHD. The relatives showed a direct correlation between serum cholesterol and SCBR upto serum cholesterol level of 220 mg/dl, but the correlation was lost beyond this level. The critical levels for predicting risk of IHD were 30 mg/dl for SCBR and 8 for cholesterol: SCBR ratio. The latter was found to be a more sensitive index for predicting the risk of IHD as compared to SCBR alone.

摘要

对50名健康受试者、25例缺血性心脏病(IHD)患者及其70名无症状的一级亲属进行了血清总胆固醇和血清胆固醇结合储备(SCBR)的评估。在正常受试者中,SCBR的平均值倾向于随着血清胆固醇水平的升高而增加,而在IHD患者中这种关系则相反。亲属在血清胆固醇水平达到220mg/dl之前,血清胆固醇与SCBR呈直接相关,但超过该水平后这种相关性消失。预测IHD风险的临界值为SCBR 30mg/dl和胆固醇:SCBR比值8。与单独的SCBR相比,后者被发现是预测IHD风险更敏感的指标。

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