Dermatology Department, Morvan University Hospital, Brest, France.
J Eur Acad Dermatol Venereol. 2013 Aug;27 Suppl 3:30-5. doi: 10.1111/jdv.12164.
The association between alcohol consumption and psoriasis has been frequently discussed since the 1980s, but no systematic review has been elaborated on the subject so far. The aim of this systematic literature review was to assess whether alcohol consumption is more prevalent in psoriasis patients than in the general population and whether alcohol consumption is a risk factor of psoriasis. A systematic literature search was carried out in the Medline, Embase and Cochrane databases using the keywords 'psoriasis' AND 'alcohol drinking' OR 'alcohol-related disorders'. The search was then enlarged with the keywords 'psoriasis' AND 'risk factor' OR 'comorbidity'. Altogether 911 references in English and French were found. Out of these, 837 articles were excluded by reading the abstract and 46 by reading the article. A total of 28 articles were selected. Alcohol consumption in psoriasis patients versus the general population: 23 studies were selected; 18 concluded that alcohol consumption was more prevalent in psoriasis patients, and 5 did not. Three studies compared the prevalence of excessive drinking using a questionnaire on alcohol dependence (CAGE or Self-administered alcohol screening test (SAAST)) or with quantitative criteria for excessive drinking. In these studies, excessive drinking was more prevalent among psoriasis patients than in the general population. Other articles studied the quantity and type of alcohol consumed. In 11 studies, psoriasis patients consumed more alcohol than the controls. Four other studies showed excessive alcohol consumption in psoriasis patients without control group comparison. Conversely, five studies identified no difference in alcohol consumption between psoriasis patients and the general population. The heterogeneity in the measurement of alcohol consumption did not allow performing meta-analysis. Alcohol as a risk factor for psoriasis: only five studies were selected. In four of these studies alcohol was found to be a risk factor for psoriasis. Alcohol consumption seems to be greater in psoriasis patients than in the general population. However, there is not enough evidence to establish whether alcohol consumption is indeed a risk factor for psoriasis.
自 20 世纪 80 年代以来，人们经常讨论饮酒与银屑病之间的关系，但迄今为止尚未对此主题进行系统评价。本系统文献回顾的目的是评估饮酒在银屑病患者中是否比在普通人群中更为普遍，以及饮酒是否是银屑病的一个危险因素。我们在 Medline、Embase 和 Cochrane 数据库中使用了“银屑病”和“饮酒”或“酒精相关障碍”的关键词进行了系统的文献搜索。然后，我们使用了“银屑病”和“危险因素”或“共病”的关键词来扩大搜索范围。共发现 911 篇英文和法文参考文献。其中，837 篇通过阅读摘要被排除，46 篇通过阅读全文被排除。共选择了 28 篇文章。银屑病患者与普通人群的饮酒情况：选择了 23 项研究；其中 18 项研究得出结论，饮酒在银屑病患者中更为普遍，而 5 项研究则得出相反的结论。有 3 项研究使用酒精依赖问卷（CAGE 或自我管理酒精筛查测试（SAAST））或使用过量饮酒的定量标准比较了过量饮酒的患病率。在这些研究中，银屑病患者的过量饮酒比普通人群更为普遍。其他文章研究了饮酒的数量和类型。在 11 项研究中，银屑病患者的饮酒量多于对照组。另外 4 项研究表明，与对照组相比，银屑病患者存在过度饮酒的情况。相反，有 5 项研究发现银屑病患者和普通人群之间的饮酒量没有差异。由于饮酒量的测量存在异质性，因此无法进行荟萃分析。酒精作为银屑病的一个危险因素：仅选择了 5 项研究。其中 4 项研究发现酒精是银屑病的一个危险因素。饮酒似乎在银屑病患者中比在普通人群中更为普遍。然而，目前尚无足够的证据表明饮酒确实是银屑病的一个危险因素。
