Chun S I, Su W P, Lee S
Department of Dermatology, Yonsei University College of Medicine, Seoul, Korea.
J Dermatol. 1990 Jun;17(6):333-41. doi: 10.1111/j.1346-8138.1990.tb01653.x.
Light microscopic studies of 55 patients with complete and incomplete types of Behçet's syndrome were reviewed. We reported here 39 skin biopsies from 30 patients with cutaneous lesions of oral, and genital ulcers, folliculitis, erythema multiforme, and thrombophlebitis. Leukocytoclastic vasculitis was seen in 5 of 12 (42%) cases of oral ulcers and 2 of 7 (29%) of genital ones. Lymphocytic vasculitis was demonstrated in 3 of 12 (25%) cases of oral ulcers and 4 of 7 (57%) of genital ulcers. However, the vasculitis was observed only locally in the areas with moderate or severe inflammation. From the biopsy specimens of our cases with fully developed mucocutaneous lesions of Behçet's syndrome, it appears that the forms of vasculitis that are often emphasized in the literature are a phenomenon secondary to the intense inflammation seen in such cutaneous lesions.
回顾了55例完全型和不完全型白塞病患者的光镜研究。我们在此报告了30例有皮肤病变（包括口腔和生殖器溃疡、毛囊炎、多形红斑和血栓性静脉炎）患者的39份皮肤活检结果。在12例口腔溃疡患者中有5例（42%）出现白细胞破碎性血管炎，7例生殖器溃疡患者中有2例（29%）出现。在12例口腔溃疡患者中有3例（25%）出现淋巴细胞性血管炎，7例生殖器溃疡患者中有4例（57%）出现。然而，血管炎仅在中度或重度炎症区域局部观察到。从我们患有完全发展的白塞病黏膜皮肤病变的病例活检标本来看，文献中经常强调的血管炎形式似乎是此类皮肤病变中强烈炎症继发的一种现象。
