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骨盆骨折患者骨盆血管造影栓塞后的急性并发症。

Acute complications of patients with pelvic fractures after pelvic angiographic embolization.

机构信息

UCSF/SFGH Orthopaedic Trauma Institute, 2550 23rd Street, San Francisco, CA 94110, USA.

出版信息

Clin Orthop Relat Res. 2013 Sep;471(9):2906-11. doi: 10.1007/s11999-013-3119-z.

Abstract

BACKGROUND

Hemodynamically unstable patients with a pelvic fracture and arterial pelvic bleeding frequently are treated with pelvic angiographic embolization (PAE). PAE is reported to be a safe and effective method of controlling hemorrhage. However, the loss of blood supply and subsequent ischemia from embolization may lead to adverse consequences.

OBJECTIVES/PURPOSES: We sought to determine (1) the frequency and types of complications observed after PAE; (2) the mortality after PAE; and (3) the clinical factors associated with complications and mortality after PAE.

METHODS

We conducted a retrospective case series descriptive study at a Level I trauma center. Using our institution's trauma registry, we isolated patients with pelvic fractures treated with PAE admitted between June 1999 and December 2007. Complications attributed to PAE occurring in the initial hospital stay were recorded. We identified 98 patients with pelvic fractures treated by PAE with an average hospital stay of 25.3 days.

RESULTS

The complication rate was 11% and included six patients with gluteal muscle necrosis (6%), five with surgical wound breakdown (5%), four deep infections (4%), one superficial infection, two patients with of impotence (2%), and one with bladder necrosis. The mortality rate in the PAE group reached 20%. Bilateral embolization was performed in 100% of the patients with complications. Nonselective embolization was performed in 81% of patients with complications. All of the patients with gluteal necrosis had bilateral nonselective embolization.

CONCLUSIONS

Bilateral or nonselective PAE is associated with significant complications during the initial hospital stay. The value of PAE should be weighed against its possible adverse consequences. Selective unilateral arterial embolization should be considered whenever possible.

摘要

背景

血流动力学不稳定伴骨盆骨折和动脉性骨盆出血的患者常需接受骨盆血管造影栓塞术(PAE)治疗。有报道称,PAE 是一种安全有效的控制出血方法。然而,栓塞导致的血供损失和随后的组织缺血可能会产生不良后果。

目的

我们旨在确定:(1)PAE 后观察到的并发症的频率和类型;(2)PAE 后的死亡率;以及(3)与 PAE 后并发症和死亡率相关的临床因素。

方法

我们在一家一级创伤中心进行了回顾性病例系列描述性研究。我们使用机构创伤登记处,筛选了 1999 年 6 月至 2007 年 12 月期间接受 PAE 治疗的骨盆骨折患者。记录初始住院期间归因于 PAE 的并发症。我们确定了 98 例接受 PAE 治疗的骨盆骨折患者,平均住院时间为 25.3 天。

结果

并发症发生率为 11%,包括 6 例(6%)臀肌坏死、5 例(5%)手术切口破裂、4 例(4%)深部感染、1 例(1%)浅部感染、2 例(2%)阳痿和 1 例(1%)膀胱坏死。PAE 组的死亡率为 20%。有并发症的患者均行双侧栓塞,81%的患者行非选择性栓塞。所有臀肌坏死的患者均行双侧非选择性栓塞。

结论

双侧或非选择性 PAE 与初始住院期间发生严重并发症相关。PAE 的价值应与其可能的不良后果权衡。只要有可能,应考虑选择性单侧动脉栓塞。

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