Shahrokni Armin, Saif Muhammad Wasif
University of California. Los Angeles, CA, USA.
JOP. 2013 Jul 10;14(4):391-4. doi: 10.6092/1590-8577/1663.
Due to pancreatic cancer's dismal prognosis, much of management is focused upon palliation and symptom management, and the decision to treat a patient with more aggressive maneuvers must always take into account the impact upon a patient's quality of life. In addition, majority of the patients with advanced pancreatic cancer are elderly. Oncologists are challenged to make tough treatment decisions. Many elderly patients cannot tolerate side effects of chemotherapy, especially the combination regimens. Despite that many patients continue to receive chemotherapy even in the last month of their lives. The effect of referral to palliative care on health-related outcome especially for patients with poor quality of life is still not very clear. The authors will review abstracts that have focused on these fields that were presented at the Annual Meeting of ASCO 2013 (Abstracts #4009, #4053, #6607, #9518, #9538, #9539, #9546, and #9638).
由于胰腺癌预后不佳，其治疗大多聚焦于缓解症状和对症处理，决定对患者采取更积极的治疗措施时必须始终考虑对患者生活质量的影响。此外，大多数晚期胰腺癌患者为老年人。肿瘤学家面临着做出艰难治疗决策的挑战。许多老年患者无法耐受化疗的副作用，尤其是联合治疗方案。尽管如此，许多患者甚至在生命的最后一个月仍继续接受化疗。转诊至姑息治疗对健康相关结局的影响，尤其是对生活质量较差的患者，目前仍不太明确。作者将回顾在2013年美国临床肿瘤学会年会上发表的聚焦于这些领域的摘要（摘要编号#4009、#4053、#6607、#9518、#9538、#9539、#9546和#9638）。
