Bhama Jay K, Bansal Aditya, Shigemura Norihisa, Bermudez Christian A, Toyoda Yoshiya
Division of Cardiac Surgery, Department of Cardiothoracic Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.
Interact Cardiovasc Thorac Surg. 2013 Nov;17(5):835-7. doi: 10.1093/icvts/ivt305. Epub 2013 Jul 11.
A sternal-sparing approach for bilateral lung transplantation was recently applied to reoperative lung transplant cases and is compared with the traditional clamshell approach.
A retrospective analysis of 15 consecutive reoperative bilateral lung transplants performed from January 2008 to April 2011 was conducted. Outcomes were compared between the first 11 patients who underwent the traditional clamshell and the most recent 4 patients who underwent the sternal-sparing approach.
The indication for retransplantation was obliterative bronchiolitis in all patients. Both groups were similar with regard to age, allograft ischaemic time and operative time. Cardiopulmonary bypass was more frequent in the sternal-sparing group although required for a shorter period of time. The need for postoperative extracorporeal membrane oxygenation for primary graft dysfunction was similar in both groups. The length of ICU care and total hospitalization length of stay were similar for the sternal-sparing group compared with the traditional clamshell approach. Operative mortality and overall survival also did not differ.
Reoperative bilateral lung transplantation with a sternal-sparing approach is feasible and may yield outcomes similar to those in the traditional clamshell approach. Further analysis with larger numbers of patients is warranted to delineate the benefits of this approach for patients requiring reoperative lung transplantation.
一种保留胸骨的双侧肺移植方法最近应用于再次肺移植病例,并与传统的蚌式切口方法进行比较。
对2008年1月至2011年4月连续进行的15例再次双侧肺移植进行回顾性分析。比较了前11例行传统蚌式切口的患者和最近4例行保留胸骨方法的患者的结果。
所有患者再次移植的指征均为闭塞性细支气管炎。两组在年龄、移植肺缺血时间和手术时间方面相似。保留胸骨组体外循环更频繁,但所需时间较短。两组因原发性移植肺功能障碍而需要术后体外膜肺氧合的情况相似。与传统蚌式切口方法相比,保留胸骨组的重症监护病房护理时间和总住院时间相似。手术死亡率和总体生存率也没有差异。
采用保留胸骨方法进行再次双侧肺移植是可行的,其结果可能与传统蚌式切口方法相似。需要对更多患者进行进一步分析,以明确这种方法对需要再次肺移植患者的益处。